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Merck
CN

SBR00067

Rifampicin Water Soluble

greener alternative

solubility: 50 mg/mL in water, freely soluble

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关于此项目

NACRES:
NA.76
UNSPSC Code:
51283601
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form

solid

Quality Segment

specific activity

(Antibacterial)

sustainability

Greener Alternative Product

solubility

water: freely soluble 50 mg/mL

antibiotic activity spectrum

Gram-negative bacteria, Gram-positive bacteria, mycobacteria, viruses

greener alternative category

mode of action

protein synthesis | interferes

storage temp.

−20°C

General description

Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. Rifampicin is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, and primary biliary cirrhosis (PBC). Rifampicin was also found active by inhibiting Tau Oligomer Propagation in Alzheimer’s disease. In addition, Rifampicin is used as a selection agent for agrobacterium mediated plant transformation.
We are committed to bringing you Greener Alternative Products. This product is a Design for Sustainability (DfS) developed product, which belongs to one of the four categories of greener alternatives. Click here to view its DfS scorecard.

Application

Rifampicin is used to treat Tuberculosis and Tuberculosis-related mycobacterial infections. It is widely used as an antipruritic agent in the autoimmune cholestatic liver disease, primary biliary cirrhosis (PBC). It has been shown to cause hepatitis.

Biochem/physiol Actions

Rifampicin inhibits the assembly of DNA and protein into mature virus particles. It inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase, which results in cell death.

Mode of Action: Inhibits initiation of RNA synthesis by binding to β-subunit of RNA polymerase. Inhibits the assembly of DNA and protein into mature virus particles.


pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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