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经验公式(希尔记法):
C35H46ClN5O9S
化学文摘社编号:
分子量:
748.29
UNSPSC Code:
51101500
MDL number:
NACRES:
NA.41
产品名称
Asunaprevir, ≥99% (HPLC), powder
InChI key
XRWSZZJLZRKHHD-QGQNBIQGSA-N
InChI
1S/C35H46ClN5O9S/c1-9-19-16-35(19,31(44)40-51(46,47)22-11-12-22)39-28(42)25-15-21(49-29-24-14-20(36)10-13-23(24)26(48-8)17-37-29)18-41(25)30(43)27(33(2,3)4)38-32(45)50-34(5,6)7/h9-10,13-14,17,19,21-22,25,27H,1,11-12,15-16,18H2,2-8H3,(H,38,45)(H
SMILES string
CC(C)(C)[C@@H](C(=O)N1C[C@@H](C[C@H]1C(=O)N[C@@]2(C[C@H]2C=C)C(=O)NS(=O)(=O)C3CC3)OC4=NC=C(C5=C4C=C(C=C5)Cl)OC)NC(=O)OC(C)(C)C
assay
≥99% (HPLC)
form
powder
color
white to off-white
antibiotic activity spectrum
viruses
mode of action
protein synthesis | inhibits
storage temp.
−20°C (−15°C to −25°C)
Quality Level
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Biochem/physiol Actions
Asunaprevir is a direct acting antiviral agent that inhibits the NS3/4A protease of the hepatitis C virus (HCV). Inhibition of the NS3/4A protease prevents viral replication and leads to the clearance of HCV from the body. Asunaprevir is active again viruses.
General description
Asunaprevir is a competitive inhibitor of HCV NS3/4A protease which act by inhibiting the protease activity of the NS3/4A enzyme of the hepatitis C virus.
signalword
Warning
hcodes
pcodes
Hazard Classifications
STOT RE 2
target_organs
Liver
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
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