质量水平
方案
≥97% (HPLC)
表单
powder
储存条件
under inert gas (Nitrogen)
颜色
white
抗生素抗菌谱
Gram-negative bacteria
作用机制
enzyme | inhibits
运输
ambient
储存温度
−20°C
SMILES字符串
C1C[C@H](N2C[C@@H]1N(C2=O)OS(=O)(=O)[O-])C(=O)N.[Na+]
InChI
InChI=1S/C7H11N3O6S.Na/c8-6(11)5-2-1-4-3-9(5)7(12)10(4)16-17(13,14)15;/h4-5H,1-3H2,(H2,8,11)(H,13,14,15);/q;+1/p-1/t4-,5+;/m1./s1
InChI key
RTCIKUMODPANKX-JBUOLDKXSA-M
一般描述
Avibactam sodium is a β-lactamase inhibitor and β-Lactamases are responsible for resistance to penicillins, monobactams, carbapenems, and extended-spectrum cephalosporins. It is a synthetic molecule with activity against gram-negative bacteria.
应用
Avibactam and related compounds have been studied for their ability to inhibit a variety of beta-lactamases, which are enzymes that inactivate beta-lactam antibiotics such as penicillin. The development of new beta-lactamase inhibitors like Avibactam is important for combating antibiotic resistance.
生化/生理作用
Avibactam is a β-lactamase inhibitor which inhibits the activity of β-lactamases by binding to the active site of β-lactamases and blocks the access of the substrate to the enzyme. Avibactam is effective against bacteria resistant to ceftazidime like Escherichia coli.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
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