Quality Segment
assay
≥95% (H-NMR)
form
powder
color
white to off-white
antibiotic activity spectrum
viruses
mode of action
DNA synthesis | inhibits
storage temp.
2-8°C
SMILES string
CC1=CC(=C(C(=C1)C)NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C
InChI
1S/C20H19N5/c1-13-10-14(2)19(15(3)11-13)24-18-8-9-22-20(25-18)23-17-6-4-16(12-21)5-7-17/h4-11H,1-3H3,(H2,22,23,24,25)
InChI key
ILAYIAGXTHKHNT-UHFFFAOYSA-N
General description
Dapivirine is an antibiotic from a class of nn-nucleoside reverse transcriptase inhibitor compounds. Dapivirine, a substituted diarylpyrimidine derivative, irreversibly binds to and inhibits HIV reverse transcriptase which prevents the conversion of viral RNA to proviral DNA.
Biochem/physiol Actions
Dapivirine is a diarylpyrimidine non-nucleoside reverse transcriptase inhibitor and has activity against wild-type virus strains and strains harboring different NNRTI resistance-inducing mutations.
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable