Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
dry media
color
white to off-white
antibiotic activity spectrum
mycobacteria
mode of action
cell wall synthesis | inhibits
shipped in
ambient
storage temp.
−20°C
SMILES string
C[C@@]1(CN2C=C(N=C2O1)[N+](=O)[O-])COC3=CC=C(C=C3)N4CCC(CC4)OC5=CC=C(C=C5)OC(F)(F)F
InChI
InChI=1S/C25H25F3N4O6/c1-24(15-31-14-22(32(33)34)29-23(31)38-24)16-35-18-4-2-17(3-5-18)30-12-10-20(11-13-30)36-19-6-8-21(9-7-19)37-25(26,27)28/h2-9,14,20H,10-13,15-16H2,1H3/t24-/m1/s1
InChI key
XDAOLTSRNUSPPH-XMMPIXPASA-N
General description
Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall. A limitation of dasabuvir is the lower potential for cross-genotypic activity as the binding sites are poorly preserved across HCV genotypes.
Biochem/physiol Actions
Delamanid is an antimycobacterial agent that inhibits mycolic acid synthesis, an essential component of the cell wall of Mycobacterium tuberculosis. Inhibition of mycolic acid synthesis leads to the disruption of cell wall structure and integrity, and ultimately, bacterial cell death.
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警示词
Warning
危险代码
Hazard Classifications
Repr. 2
存储类别
11 - Combustible Solids
怎么回事？
WGK 3
闪点 (F)
Not applicable
闪点 (°C)
Not applicable