主要文件

查看所有文档

SBR00079

Delamanid

Name: Delamanid
Brand: SIGMA

≥98% (HPLC), powder

别名:

OPC-67683

登录查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:

C₂₅H₂₅F₃N₄O₆

化学文摘社编号:

681492-22-8

分子量:

534.48

UNSPSC Code:

51101500

NACRES:

NA.41

技术服务

需要帮助？我们经验丰富的科学家团队随时乐意为您服务。

让我们为您提供帮助

属性

Quality Level

100

assay

≥98% (HPLC)

form

powder

storage condition

dry media

color

white to off-white

antibiotic activity spectrum

mycobacteria

mode of action

cell wall synthesis | inhibits

shipped in

ambient

storage temp.

−20°C

SMILES string

C[C@@]1(CN2C=C(N=C2O1)[N+](=O)[O-])COC3=CC=C(C=C3)N4CCC(CC4)OC5=CC=C(C=C5)OC(F)(F)F

InChI

InChI=1S/C25H25F3N4O6/c1-24(15-31-14-22(32(33)34)29-23(31)38-24)16-35-18-4-2-17(3-5-18)30-12-10-20(11-13-30)36-19-6-8-21(9-7-19)37-25(26,27)28/h2-9,14,20H,10-13,15-16H2,1H3/t24-/m1/s1

InChI key

XDAOLTSRNUSPPH-XMMPIXPASA-N

说明

General description

Delamanid is an anti-tuberculosis agent derived from the nitro-dihydro-imidazooxazole class of compounds that inhibits mycolic acid synthesis of bacterial cell wall. A limitation of dasabuvir is the lower potential for cross-genotypic activity as the binding sites are poorly preserved across HCV genotypes.

Biochem/physiol Actions

Delamanid is an antimycobacterial agent that inhibits mycolic acid synthesis, an essential component of the cell wall of Mycobacterium tuberculosis. Inhibition of mycolic acid synthesis leads to the disruption of cell wall structure and integrity, and ultimately, bacterial cell death.

Still not finding the right product?

Explore all of our products under

pictograms

GHS08

signalword

Warning

hcodes

H361d

pcodes

P201 - P202 - P280 - P308 + P313 - P405 - P501

Hazard Classifications

Repr. 2

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c