方案
≥98% (HPLC)
质量水平
表单
powder
颜色
white to off-white
抗生素抗菌谱
viruses
作用机制
enzyme | inhibits
储存温度
−20°C
SMILES字符串
C[C@@H]1CCO[C@@H]2N1C(=O)C3=C(C(=O)C(=CN3C2)C(=O)NCC4=C(C=C(C=C4)F)F)O
InChI
1S/C20H19F2N3O5/c1-10-4-5-30-15-9-24-8-13(17(26)18(27)16(24)20(29)25(10)15)19(28)23-7-11-2-3-12(21)6-14(11)22/h2-3,6,8,10,15,27H,4-5,7,9H2,1H3,(H,23,28)/t10-,15+/m1/s1
InChI key
RHWKPHLQXYSBKR-BMIGLBTASA-N
一般描述
Dolutegravir is an antibioitic which belongs to the class of compounds known as integrase strand transfer inhibitors (INSTIs).
生化/生理作用
Dolutegravir inhibits HIV-1 viral replication, high potency against the HIV-1 Y143R, N155H, and G140S/Q148H mutants. Dolutegravir inhibitis the action of the HIV integrase enzyme, which is necessary for the integration of viral DNA into the host genome, thereby preventing viral replication and reducing HIV viral load.
警示用语:
Warning
危险声明
预防措施声明
危险分类
Aquatic Acute 1 - Aquatic Chronic 1
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
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