SBR00088
Rilpivirine
≥95% (HPLC), powder
别名:
4-[[4-[[4-[(1E)-2-Cyanoethenyl]-2,6-dimethylphenyl]amino]-2-pyrimidinyl]amino]benzonitrile, R 278474, TMC 278
质量水平
方案
≥95% (HPLC)
表单
powder
颜色
white to yellow, or beige
抗生素抗菌谱
viruses
作用机制
enzyme | inhibits
运输
ambient
储存温度
−20°C
SMILES字符串
CC1=CC(=CC(=C1NC2=NC(=NC=C2)NC3=CC=C(C=C3)C#N)C)/C=C/C#N
InChI
1S/C22H18N6/c1-15-12-18(4-3-10-23)13-16(2)21(15)27-20-9-11-25-22(28-20)26-19-7-5-17(14-24)6-8-19/h3-9,11-13H,1-2H3,(H2,25,26,27,28)/b4-3+
InChI key
YIBOMRUWOWDFLG-ONEGZZNKSA-N
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一般描述
Rilpivirine is an antibiotic which belongs to the class of compounds known as non-nucleoside reverse transcriptase inhibitors (NNRTIs).
生化/生理作用
Nonnucleoside reverse transcriptase inhibitor (NNRTI); anti-retroviral
Rilpivirine inhibits the activity of the reverse transcriptase enzyme, which is essential for the replication of HIV-1. Specifically, it binds to a specific site on the enzyme and blocks its activity, thereby preventing the conversion of viral RNA into DNA, which is an essential step for the integration of viral DNA into host cells.
Rilpivirine is a next generation nonnucleoside reverse transcriptase inhibitor (NNRTI), It has been shown to be active against many HIV strains with mutations that confer resistance to the first-generation NNRTIs.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
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