质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to off-white
作用机制
protein synthesis | inhibits
储存温度
2-30°C
SMILES字符串
CCN(C1CCOCC1)C2=CC(=CC(=C2C)C(=O)NCC3=C(C=C(NC3=O)C)C)C4=CC=C(C=C4)CN5CCOCC5
InChI
InChI=1S/C34H44N4O4/c1-5-38(29-10-14-41-15-11-29)32-20-28(27-8-6-26(7-9-27)22-37-12-16-42-17-13-37)19-30(25(32)4)33(39)35-21-31-23(2)18-24(3)36-34(31)40/h6-9,18-20,29H,5,10-17,21-22H2,1-4H3,(H,35,39)(H,36,40)
InChI key
NSQSAUGJQHDYNO-UHFFFAOYSA-N
一般描述
Tazemetostat is a small molecule inhibitor of the EZH2 protein, which is a histone-lysine N-methyltransferase enzyme that plays a key role in epigenetic regulation of gene expression.
生化/生理作用
Tazemetostat inhibits the EZH2 protein. EZH2 is a histone-lysine N-methyltransferase enzyme that plays a key role in epigenetic regulation of gene expression in cells. As an epigenetic modifier, EZH2 protein controls the transcriptional repression of various genes involved in cell cycle regulation, DNA repair, and other cellular processes.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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