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Merck
CN

SCP0003

Proteasome Substrate 1, fluorogenic

≥95% (HPLC), lyophilized

别名:

Z-LLL-AMC, Z-Leu-Leu-Leu-AMC

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关于此项目

经验公式(希尔记法):
C36H48N4O7
分子量:
648.79
UNSPSC Code:
12352200
NACRES:
NA.32
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产品名称

Proteasome Substrate 1, fluorogenic,

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥80%

storage condition

protect from light

storage temp.

−20°C

Biochem/physiol Actions

Z-Leu-Leu-Leu-AMC is a fluorogenic substrate for measuring the chymotrypsin-like peptidase activity of the 20S proteasome.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Oriane Tasta et al.
Free radical biology & medicine, 164, 303-314 (2021-01-16)
Premature placental senescence is a hallmark of pregnancy-related disorders such as intrauterine growth restriction (IUGR) and preeclampsia (PE), two major cause of maternal and neonatal morbidity and mortality. Oxidative stress and lipid peroxidation are involved in the pathogenesis of PE
S Tsubuki et al.
Biochemical and biophysical research communications, 196(3), 1195-1201 (1993-11-15)
A tripeptide aldehyde protease inhibitor, benzyloxycarbonyl(Z)-Leu-Leu-leucinal (ZLLLa1), initiates neurite outgrowth in PC12 cells at an optimal concentration of 30nM. This result suggests the existence of a protease which regulates neurite formation in PC12 cells. We report here an attempt to

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