产品名称
MG-115 / ASD 4955,
方案
≥95% (HPLC)
表单
lyophilized
组成
Peptide Content, ≥80%
储存条件
protect from light
储存温度
−20°C
Amino Acid Sequence
Z-Leu-Leu-Nva-al
应用
MG-115 (Z-Leu-Leu-Nva-al) is used as a selective proteosome inhibitor.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
常规特殊物品
此项目有
Yolanda Pérez-Pertejo et al.
Parasitology, 138(9), 1082-1092 (2011-08-05)
Methionine adenosyltransferase (MAT) is an important enzyme for metabolic processes, to the extent that its product, S-adenosylmethionine (AdoMet), plays a key role in trans-methylation, trans-sulphuration and polyamine synthesis. Previous studies have shown that a MAT-overexpressing strain of Leishmania donovani controls
Estabelle Ang et al.
Journal of cellular physiology, 220(2), 450-459 (2009-04-15)
Proteasome inhibitors represent a promising therapy for the treatment of relapsed and/or refractory multiple myeloma, a disease that is concomitant with osteolysis and enhanced osteoclast formation. While blockade of the proteosome pathway has been recently shown to influence osteoclast formation
Karim Harhouri et al.
EMBO molecular medicine, 9(9), 1294-1313 (2017-07-05)
Hutchinson-Gilford progeria syndrome (HGPS) is a lethal premature and accelerated aging disease caused by a de novo point mutation in LMNA encoding A-type lamins. Progerin, a truncated and toxic prelamin A issued from aberrant splicing, accumulates in HGPS cells' nuclei
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