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Merck
CN

SCP0008

[DArg0,Hyp3,Thi5,8,DPhe7]-Adamantaneacetyl Bradykinin

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关于此项目

经验公式(希尔记法):
C68H99N19O14S2
分子量:
1470.76
NACRES:
NA.32
UNSPSC Code:
12352209
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assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥70%

storage condition

protect from light

storage temp.

−20°C

Application

Bradykinin, a nonapeptide, is a potent endothelium-dependent vasodilator that operates via bradykinin receptors B1 and B2. Adamantaneacetyl Bradykinin (NA-BK) and [DArg0,Hyp3,Thi5,8,DPhe7]-Adamantaneacetyl Bradykinin are used as a B2 bradykinin receptor antagonists.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Galia K Soukhova-O'Hare et al.
Life sciences, 78(17), 1990-1997 (2005-11-18)
Endogenous bradykinin (BK) is an established mediator of pulmonary inflammation, yet its role in lung disease is unclear. In the rabbit, injecting BK into the lung parenchyma elicits reflex hyperpnea, tachypnea, hypotension, and bradycardia by stimulating pulmonary sympathetic afferents. To
W D Ehringer et al.
Inflammation, 21(3), 279-298 (1997-06-01)
alpha-Thrombin (AT) and bradykinin (BK) are endogenous mediators that are released during an inflammatory response, and could have a synergistic effect on endothelial permeability. Human umbilical vein endothelial cells (HUVEC) were grown on Transwell membranes and then tested for alterations

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