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Merck
CN

SCP0037

Sigma-Aldrich

淀粉样蛋白β1-40大鼠

≥95% (HPLC)

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关于此项目

经验公式(希尔记法):
C190H291N51O57S1
分子量:
4233.72
UNSPSC代码:
12352200
NACRES:
NA.32
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方案

≥95% (HPLC)

表单

lyophilized

组成

Peptide Content, ≥75%

储存条件

protect from light

储存温度

−20°C

Amino Acid Sequence

Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val

应用

淀粉样β(Aβ)是指衍生自淀粉样蛋白前体蛋白的肽,其长度在36-43个氨基酸之间变化。 Aβ(s)肽,其肽片段和突变片段用于研究广泛的代谢和调节功能,包括激酶的激活、胆固醇转运的调节、作为转录因子的功能和炎症的调节因子。 Aβ(s)肽及其肽片段还用于研究氧化应激、金属结合和蛋白质交联机制,例如阿尔茨海默病和神经变性。

储存分类代码

11 - Combustible Solids

WGK

WGK 1

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

常规特殊物品
此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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The journal of physical chemistry. B, 114(34), 11261-11271 (2010-08-10)
There is no consensus on the coordinating ligands for Cu(2+) by Abeta. However, the differences in peptide sequence between human and rat have been hypothesized to alter metal ion binding in a manner that alters Cu(2+)-induced aggregation of Abeta. Herein
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