产品名称
Calpastatin Peptide Ac 184-210, ≥95% (HPLC)
assay
≥95% (HPLC)
form
lyophilized
composition
Peptide Content, ≥75%
storage condition
protect from light
storage temp.
−20°C
Application
Calpastatin Peptide Ac 184-210 has been used as the endogenous calpain inhibitor to study its effects on myristoylated alanine-rich C kinase substrate (MARCKS) cleavage in mouse kidney cells. It has also been used as a calpain inhibitor to examine its effects on the formation of DNA-platinum adducts by cisplatin (CDDP) in neuronal cells.
Biochem/physiol Actions
Calpastatin, located in the cytosol, is involved in selective protein cleavage in response to calcium signaling.
Calpastatin, a component of the calpain/calpastatin system, is a calpain (calcium-dependent cysteine protease) inhibitor. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation.
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable