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Merck
CN

SCP0117

Cionin Peptide

≥95% (HPLC), lyophilized powder

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关于此项目

经验公式(希尔记法):
C53H63N11O19S3
分子量:
1254.32
UNSPSC Code:
12352202
NACRES:
NA.32
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产品名称

Cionin,

assay

≥95% (HPLC)

form

lyophilized

composition

Peptide Content, ≥85%

storage condition

protect from light

storage temp.

−20°C

Application

Protochordean octapeptide cionin is a structural hybrid of mammalian cholecystokinin (CCK) and gastrin with functions most similar to those of CCK. Cionin is used as a potent and efficient stimulator of gastric histamine release and acid secretion via a CCK-B receptor.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品
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历史批次信息供参考:

分析证书(COA)

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Tsuyoshi Kawada et al.
Zoological science, 27(2), 134-153 (2010-02-10)
The critical phylogenetic position of ascidians leads to the presumption that neuropeptides and hormones in vertebrates are highly likely to be evolutionarily conserved in ascidians, and the cosmopolitan species Ciona intestinalis is expected to be an excellent deuterostome Invertebrate model
B Schjoldager et al.
The American journal of physiology, 260(6 Pt 1), G976-G982 (1991-06-01)
The protochordean octapeptide cionin is structurally a hybrid of mammalian cholecystokinin (CCK) and gastrin, and thus their possible common ancestor. To determine whether cionin behaves like CCK or gastrin, we examined its effect on canine fundic somatostatin cells and on
Stimulation by the ancestral member of the CCK/gastrin family, cionin, of trout gallbladder contraction.
A H Johnsen et al.
Annals of the New York Academy of Sciences, 713, 404-406 (1994-03-23)
R Mårvik et al.
Scandinavian journal of gastroenterology, 29(7), 591-594 (1994-07-01)
The protochordean octapeptide cionin is structurally a hybrid of mammalian cholecystokinin (CCK) and gastrin. An earlier study has shown that cionin in mammals stimulates gallbladder contraction and gastric somatostatin release, similarly to CCK-8. In the present study we examined the

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