产品名称
Cyclopenol, ≥95% (LC/MS-ELSD)
SMILES string
N1([C@@]3(O[C@@H]3c4cc(ccc4)O)C(=O)Nc2c(cccc2)C1=O)C
InChI
1S/C17H14N2O4/c1-19-15(21)12-7-2-3-8-13(12)18-16(22)17(19)14(23-17)10-5-4-6-11(20)9-10/h2-9,14,20H,1H3,(H,18,22)/t14-,17+/m1/s1
InChI key
BDDNYDPRCCDQQJ-PBHICJAKSA-N
assay
≥95% (LC/MS-ELSD)
form
solid
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
General description
Natural product derived from fungal source.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Jae Hak Sohn et al.
Journal of microbiology and biotechnology, 23(9), 1206-1211 (2013-06-19)
The selective inhibition of PTP1B has been widely recognized as a potential drug target for the treatment of type 2 diabetes and obesity. In the course of screening for PTP1B inhibitory fungal metabolites, the organic extracts of several fungal species
Florian Helbig et al.
Applied and environmental microbiology, 68(4), 1524-1533 (2002-03-28)
On searching for endogenous, low-molecular-weight effectors of benzodiazepine alkaloid biosynthesis in Penicillium cyclopium uric acid was isolated from ethanolic or autoclaved mycelial extracts of this fungus. The isolation was based on a three-step high-pressure liquid chromatography procedure guided by a
J C Frisvad et al.
Antonie van Leeuwenhoek, 72(2), 119-126 (1997-08-01)
The new species Penicillium discolor, frequently isolated from nuts, vegetables and cheese is described. It is characterised by rough, dark green conidia, synnemateous growth on malt agar and the production of the secondary metabolites chaetoglobosins A, B and C, palitantin
Z S Mohamed et al.
Zeitschrift fur allgemeine Mikrobiologie, 24(9), 615-618 (1984-01-01)
Balanced heterokarions were grown from Penicillium cyclopium aux-glu 1, a glutamic acid auxotroph producing benzodiazepine alkaloids of the cyclopenin-cyclopenol group, and P. viridicatum aux-met 1, a methionine auxotroph forming these alkaloids in traces only. In contrast to the hyphae of
W Lerbs et al.
Journal of basic microbiology, 25(6), 387-391 (1985-01-01)
Cyclopeptine synthetase, the key enzyme of benzodiazepine alkaloid biosynthesis in Penicillium cyclopium forms cyclo-(anthranoyl-phenylalanyl) from anthranilic acid, L-phenylalanine, the methyl group of L-methionine and ATP. The following in vitro measurable partial activities of the enzyme system were followed during the
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