SMB00081
Wogonoside
≥95% (LC/MS-ELSD)
别名:
5,7-Dihydroxy 8-methoxyflavone 7-glucuronide, Glychionide B, Oroxindin, Wogonin 7-glucuronide
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关于此项目
经验公式（希尔记法）:
C22H20O11
化学文摘社编号:
分子量:
460.39
MDL编号:
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.25
方案
≥95% (LC/MS-ELSD)
表单
solid
应用
metabolomics
vitamins, nutraceuticals, and natural products
储存温度
−20°C
SMILES字符串
COc1c(O[C@@H]2O[C@@H]([C@@H](O)[C@H](O)[C@H]2O)C(O)=O)cc(O)c3C(=O)C=C(Oc13)c4ccccc4
InChI
1S/C22H20O11/c1-30-18-13(32-22-17(27)15(25)16(26)20(33-22)21(28)29)8-11(24)14-10(23)7-12(31-19(14)18)9-5-3-2-4-6-9/h2-8,15-17,20,22,24-27H,1H3,(H,28,29)/t15-,16-,17+,20-,22+/m0/s1
InChI key
LNOHXHDWGCMVCO-NTKSAMNMSA-N
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一般描述
Natural product derived from plant source.
生化/生理作用
Wogonoside, a flavanoid, is known for its anti-inflammatory properties. Wogonoside may have therapeutic potential for use in diseases which involve the development of inflammation and angiogenesis through its inhibition of LPS-induced angiogenesis.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
法规信息
新产品
此项目有
历史批次信息供参考:
Yan Yan et al.
Chinese medicine, 13, 54-54 (2018-11-06)
Microbial fermentation has been widely applied in traditional Chinese medicine (TCM) for thousands of years in China. Various beneficial effects of fermentation for applications in TCM or herbals have been reported, such as enhanced anti-ovarian cancer, antioxidative activity, and neuroprotective
Amer Ali Abd El-Hafeez et al.
Pharmacological reports : PR, 71(2), 289-298 (2019-03-04)
Nor-wogonin, a polyhydroxy flavone, has been shown to possess antitumor activity. However, the mechanisms responsible for its antitumor activity are poorly studied. Herein, we investigated the mechanisms of nor-wogonin actions in triple-negative breast cancer (TNBC) cells. Effects of nor-wogonin on
Yan Chen et al.
Toxicology, 259(1-2), 10-17 (2009-05-12)
Wogonoside, one flavonoid derived from the root of Scutellaria baicalensis Georgi, has been reported for its anti-inflammation activity; however, whether it can inhibit inflammation-induced angiogenesis is still unclear. In the present study, we evaluated the effect of wogonoside on lipopolysaccharide
Yonglin Zhu et al.
Experimental and therapeutic medicine, 14(4), 3304-3308 (2017-10-03)
Wogonoside possesses anti-oxidative, anti-inflammatory, anti-allergy and anti-tumor properties. The aim of the present study was to evaluate whether wogonoside alleviates spinal cord injury (SCI)-induced inflammation via nuclear factor (NF)-κB and nucleotide-binding oligomerization domain-like receptor family pyrin domain containing 3 (NLRP3)
Tong Lu et al.
Journal of ethnopharmacology, 110(3), 412-418 (2006-11-18)
Huang-Lian-Jie-Du-Tang (HLJDT) is an important "heat-clearing" multiherb remedy of traditional Chinese medicine, and Radix scutellariae (Scutellaria baicalensis Georgi, Labiatae) is a key ingredient herb in it. Baicalin and wogonoside are two main effective ingredients enriched in Radix scutellariae. In the
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