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安全信息

SMB00086

Sigma-Aldrich

Columbin

≥95% (LC/MS-ELSD)

别名:

Isocolumbin

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1 MG
¥2,818.93

¥2,818.93


预计发货时间2025年11月05日详情


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1 MG
¥2,818.93

About This Item

经验公式(希尔记法):
C20H22O6
CAS Number:
分子量:
358.39
UNSPSC代码:
12352205
PubChem化学物质编号:
NACRES:
NA.25

¥2,818.93


预计发货时间2025年11月05日详情


获取大包装报价

方案

≥95% (LC/MS-ELSD)

表单

solid

应用

metabolomics
vitamins, nutraceuticals, and natural products

储存温度

−20°C

SMILES字符串

C[C@@]12C[C@H](OC(=O)[C@@H]1CC[C@]3(C)[C@H]2[C@@H]4OC(=O)[C@@]3(O)C=C4)c5ccoc5

InChI

1S/C20H22O6/c1-18-9-14(11-5-8-24-10-11)25-16(21)12(18)3-6-19(2)15(18)13-4-7-20(19,23)17(22)26-13/h4-5,7-8,10,12-15,23H,3,6,9H2,1-2H3/t12-,13+,14-,15-,18+,19+,20-/m0/s1

InChI key

AALLCALQGXXWNA-QJNFORGASA-N

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SMB00094SMB00076SMB00104
Columbin ≥95% (LC/MS-ELSD)

SMB00086

Columbin

樱桃甙 ≥95% (LC/MS-ELSD)

SMB00076

樱桃甙

form

solid

form

solid

form

solid

form

solid

assay

≥95% (LC/MS-ELSD)

assay

≥95% (LC/MS-ELSD)

assay

≥95% (LC/MS-ELSD)

assay

≥95% (LC/MS-ELSD)

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

一般描述

Natural product derived from plant source.

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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    Siddig Ibrahim Abdelwahab et al.
    European journal of pharmacology, 678(1-3), 61-70 (2012-01-10)
    Columbin, a diterpenoid furanolactone, was isolated purely for the first time from the plant species Tinspora bakis. The anti-inflammatory effects of columbin were studied in vitro, in silico and in vivo. The effect of columbin on nitric oxide was examined
    Qirong Shi et al.
    Biomedical chromatography : BMC, 21(6), 642-648 (2007-03-09)
    Columbin is an important component isolated from Radix Tinosporae. It has been demonstrated to possess many pharmacological activities, including anti-inflammation, antitumor and inhibition of enzyme activity in vivo. The purpose of the present study was to examine in vivo pharmacokinetics
    K Swaminathan et al.
    Acta crystallographica. Section C, Crystal structure communications, 45 ( Pt 2), 300-303 (1989-02-15)
    (1S,4R,5R,8S,10R,12S)-4-Hydroxy-15,16-epoxycleroda-2,12(16),14- trieno-17,12: 18,1-biscarbolactone, C20H22O6, Mr = 358.2, m.p. = 453-454 K, orthorhombic, P2(1)2(1)2(1), a = 7.3869 (6), b = 11.986 (1), c = 19.896 (2) A, V = 1761.65 A3, Z = 4, Dx = 1.351, Dm(by flotation) = 1.349
    Hiroyuki Kohno et al.
    Cancer letters, 183(2), 131-139 (2002-06-18)
    The modifying effect of dietary administration of a diterpenoid furanolactone columbin isolated from the crude drug Calumbae Radix (the root of Jateorhiza columba MIERS, Menispermacea) on azoxymethane (AOM)-induced was investigated in male F344 rats. Animals were initiated with AOM (three
    A J Nok et al.
    Journal of enzyme inhibition and medicinal chemistry, 17(1), 55-59 (2002-10-09)
    The inhibitory effects of a naturally occurring diterpenoid furanolactone, columbin, on partially purified acidic phospholipase A2 (PLA2) from Naja nigricolis was investigated. Columbin inhibited the N. nigricolis PLA2 in a dose related pattern with an IC50 value of 2.5 microM.

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