SMB00088
Oregonin
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关于此项目
经验公式（希尔记法）:
C24H30O10
化学文摘社编号:
分子量:
478.49
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352205
MDL number:
InChI
1S/C24H30O10/c25-15(5-1-13-3-7-17(26)19(28)9-13)11-16(6-2-14-4-8-18(27)20(29)10-14)34-24-23(32)22(31)21(30)12-33-24/h3-4,7-10,16,21-24,26-32H,1-2,5-6,11-12H2/t16-,21+,22-,23+,24-/m0/s1
SMILES string
OC1=CC=C(CCC(C[C@H](CCC2=CC(O)=C(O)C=C2)O[C@H]3[C@H](O)[C@@H](O)[C@H](O)CO3)=O)C=C1O
InChI key
AQRNEKDRSXYJIN-IRFILORWSA-N
form
solid
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
General description
Natural product derived from plant source.
Biochem/physiol Actions
Oregonin is a diarylheptanoid with known antioxidant, anti-cancer, and anti-inflammatory properties.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Louis C Martineau et al.
Planta medica, 76(14), 1519-1524 (2010-03-20)
Among modern day metabolic diseases, obesity has reached epidemic proportions worldwide and novel therapeutic support strategies are urgently needed. Adipocytes are interesting targets in this context. Using ethnobotanical and bioassay screening techniques, we have identified two Boreal Forest plants used
Ching-Hua Kuo et al.
Journal of pharmaceutical and biomedical analysis, 47(1), 195-200 (2008-02-05)
Oregonin, existing primarily in the Alnus plants, displayed anti-inflammatory and antioxidative activities. The capillary zone electrophoresis (CZE) method was developed in this study to quantitatively determine oregonin content in the Alnus plants for the first time. Various parameters, including buffer
Myung Joo Kang et al.
Biological & pharmaceutical bulletin, 33(1), 100-106 (2010-01-05)
To develop an external preparation of oregonin (ORG) for the treatment of atopic dermatitis (AD), conventional creams (CC) and elastic liposomes (EL) containing ORG have been formulated and examined for their in vitro skin permeation properties and in vivo therapeutic
Seong-Soo Joo et al.
Archives of pharmacal research, 25(4), 493-499 (2002-09-07)
We investigated the antitumor activity of oregonin, a diarylheptanoid derivative purified from Alnus hirsuta Turcz, Betulaceae. Oregonin is a potential novel immunomodulator, which augments the activation of natural killer (NK) cells, and thereby leads to a powerful antitumor activity. To
Eun Joo Choi et al.
International immunopharmacology, 8(5), 748-755 (2008-04-05)
Antigen-presenting dendritic cells may play an important role in the pathogenesis of inflammatory skin diseases, including atopic dermatitis. Oregonin is demonstrated to have anti-inflammatory and anti-oxidant effects. The present study was designed to assess the effect of oregonin against stimulated
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