assay
≥90% (LC/MS-ELSD)
form
solid
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
SMILES string
CC(C)c1ccc2c(CC[C@H]3[C@@](C)(CCC[C@]23C)C(O)=O)c1
InChI
1S/C20H28O2/c1-13(2)14-6-8-16-15(12-14)7-9-17-19(16,3)10-5-11-20(17,4)18(21)22/h6,8,12-13,17H,5,7,9-11H2,1-4H3,(H,21,22)/t17-,19-,20-/m1/s1
InChI key
NFWKVWVWBFBAOV-MISYRCLQSA-N
General description
脱氢枞酸（DHA 或 DAA）是一种具有生物活性的双萜类植物化学物质，存在于各种松属物种中。它是树脂酸和松香酸（AA）的衍生物。
Application
脱氢枞酸可用作以下应用的参考标准物：
- 使用傅里叶变换红外光谱（FTIR）研究松树脂的老化过程
- 通过拉曼光谱分析和红外光谱相结合的方法研究松属植物成分随年龄的变化
- 估计在地中海白松(Pinus halepensis)的化学防御中作为代替物对生物胁迫的抗性。
Biochem/physiol Actions
脱氢枞酸（DHA）具有抗癌症、抗衰老、抗菌、抗溃疡、胃保护和细胞毒性等多种生物活性。它是一种有效的抗炎剂和过氧化物酶体增殖物激活受体 α 和 γ（PPAR α/γ）的双重激活剂。DHA 具有抗衰老作用，是一种去乙酰化酶 1（SIRT 1）激活化合物。它对耐多药菌株具有抗菌特性。脱氢枞酸及其衍生物具有胃保护作用和细胞毒性作用。
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 3 Oral - Aquatic Acute 1 - Aquatic Chronic 1
存储类别
6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
wgk
WGK 1
flash_point_f
Not applicable
flash_point_c
Not applicable
Dehydroabietic acid, a diterpene, improves diabetes and hyperlipidemia in obese diabetic KK-Ay mice.
Min-Sook Kang et al.
BioFactors (Oxford, England), 35(5), 442-448 (2009-09-16)
Terpenoids, which are contained in a large number of dietary and herbal plants, have many biological effects. In this study, the effects of dehydroabietic acid (DAA), a diterpene, on glucose and lipid metabolism were examined using obese diabetic KK-Ay mice.
Xin Wan et al.
Environmental pollution (Barking, Essex : 1987), 247, 216-228 (2019-01-25)
Biomass burning (BB) is one of the largest sources of carbonaceous aerosols with adverse impacts on air quality, visibility, health and climate. BB emits a few specific aromatic acids (p-hydroxybenzoic, vanillic, syringic and dehydroabietic acids) which have been widely used
Markers, Reactions, and Interactions during the Aging of Pinus Resin Assessed by Raman Spectroscopy.
Victoria Beltran et al.
Journal of natural products, 80(4), 854-863 (2017-03-31)
The resin extracted from the species of the Pinus genus (Pinaceae family) is a widely used material. Primarily, resins are made up of two types of diterpenoids: abietanes and pimaranes. Their composition changes with aging, affecting their chemical and physical
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SMB00089-1MG | 04061837076176 |