SMB00370
四氢姜黄素
≥96% (HPLC)
别名:
四氢姜黄素, 1,7-双（4-羟基-3-甲氧基苯基）-3,5-庚二酮, HZIV 81-2, NSC687845, 四氢呋喃基甲烷
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关于此项目
经验公式（希尔记法）:
C21H24O6
化学文摘社编号:
分子量:
372.41
UNSPSC Code:
12352205
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
3485469
Quality Level
assay
≥96% (HPLC)
form
powder
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
SMILES string
COc1cc(CCC(=O)CC(=O)CCc2ccc(O)c(OC)c2)ccc1O
InChI
1S/C21H24O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h5-6,9-12,24-25H,3-4,7-8,13H2,1-2H3
InChI key
LBTVHXHERHESKG-UHFFFAOYSA-N
General description
四氢姜黄素(THC)是姜黄素的无色代谢产物。结构与姜黄素类似。THC的化学结构中不含α, β-不饱和羰基。是来源于莪术(Curcuma zedoaria)、姜笋(Zingiber mioga)和姜(Zingiber officinale)根部的天然产物。
Application
四氢姜黄素(THC)已作为神经保护剂，研究其在缺血性中风小鼠模型中改善线粒体功能障碍的治疗潜力。
Biochem/physiol Actions
四氢姜黄素的治癌作用经过充分研究，具有出色的抗癌、抗血管生成和化学预防活性。还具有抗炎性。已发现四氢姜黄素可通过缓解氧化应激发挥针对糖尿病和血管功能障碍的抗氧化和保护作用。
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存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
385.2 °F
flash_point_c
196.2 °C
Bharat B Aggarwal et al.
Molecules (Basel, Switzerland), 20(1), 185-205 (2014-12-31)
Curcumin (diferuloylmethane), a golden pigment from turmeric, has been linked with antioxidant, anti-inflammatory, anticancer, antiviral, antibacterial, and antidiabetic properties. Most of the these activities have been assigned to methoxy, hydroxyl, α,β-unsaturated carbonyl moiety or to diketone groups present in curcumin.
Nandan K Mondal et al.
Neurochemistry international, 122, 120-138 (2018-11-26)
The objectives of this study are to identify the mechanism of mitochondrial dysfunction during cerebral ischemic/reperfusion (I/R) injury and the therapeutic potential of tetrahydrocurcumin (THC) to mitigate mitochondrial dysfunction in experimental stroke model. In our study, 8-10 weeks old male
Pidaran Murugan et al.
Life sciences, 79(18), 1720-1728 (2006-06-30)
Oxidative stress has been suggested to be a contributory factor in development and complication of diabetes. In the present study, we have investigated the effect of tetrahydrocurcumin (THC), one of the active metabolites of curcumin on antioxidants status in streptozotocin-nicotinamide
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SMB00370-1G | 04061826169797 |