SMB00398
Cornin
≥98% (HPLC)
别名:
Verbenalin, Verbenaloside
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关于此项目
经验公式（希尔记法）:
C17H24O10
化学文摘社编号:
分子量:
388.37
UNSPSC Code:
12352205
NACRES:
NA.25
PubChem Substance ID:
MDL number:
Beilstein/REAXYS Number:
57895
产品名称
Cornin, ≥98% (HPLC)
InChI
1S/C17H24O10/c1-6-3-8(19)11-7(15(23)24-2)5-25-16(10(6)11)27-17-14(22)13(21)12(20)9(4-18)26-17/h5-6,9-14,16-18,20-22H,3-4H2,1-2H3/t6-,9+,10+,11-,12+,13-,14+,16-,17-/m0/s1
SMILES string
[H][C@@]12[C@@H](C)CC(=O)[C@]1([H])C(=CO[C@H]2O[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)C(=O)OC
InChI key
HLXRWTJXGMHOFN-XJSNKYLASA-N
assay
≥98% (HPLC)
form
powder
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
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Biochem/physiol Actions
Cornin is used in cardiology due to its cardioprotective property. It helps to lower blood pressure, improve heart activity, and reverse cardiac hypertrophy It can prevent lipid peroxidation catalyzed by Fe2+. Cornin can also prevent the activities of cyclooxygenase 1 (COX-1) and cyclooxygenase 1 (COX-2) enzymes. It plays a protective role against cerebral ischemia injury.
General description
Cornin is an iridoid glycoside herb. It is obtained from the fruit of Verbena Officinalis L.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Zechun Kang et al.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, 58, 340-346 (2013-05-25)
In the present study, we sought to elucidate whether Cornin contributes to induce angiogenesis and its mechanisms. To this end, we examined the role of Cornin on human brain microvascular endothelial cell line (HBMEC) proliferation, invasion, and tube formation in
Qun Zhang et al.
BMC complementary medicine and therapies, 21(1), 138-138 (2021-05-11)
Cornin is a commonly used herb in cardiology for its cardioprotective effect. The effect of herbs on the activity of cytochrome P450 enzymes (CYP450s) can induce adverse drug-drug interaction even treatment failure. Therefore, it is necessary to investigate the effect
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