SMB00584
天麻素
from Gastrodia alata, ≥98%
别名:
(2R,3S,4S,5R,6S)-2-羟甲基-6-（4-羟甲基-苯氧基）-四氢-吡喃-3,4,5-三醇, 4-β-D-吡喃葡萄糖氧苄醇, 4-羟基苯甲醇 4-O-β-D-葡萄糖苷
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关于此项目
经验公式（希尔记法）:
C13H18O7
化学文摘社编号:
分子量:
286.28
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
41116107
MDL number:
InChI key
PUQSUZTXKPLAPR-UJPOAAIJSA-N
SMILES string
O[C@@H]1[C@@H](CO)O[C@@H](OC2=CC=C(CO)C=C2)[C@H](O)[C@H]1O
InChI
1S/C13H18O7/c14-5-7-1-3-8(4-2-7)19-13-12(18)11(17)10(16)9(6-15)20-13/h1-4,9-18H,5-6H2/t9-,10-,11+,12-,13-/m1/s1
assay
≥98%
form
powder
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
2-8°C
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General description
Gastrodin, a phenolic glucoside, is the main active ingredient of the Traditional Chinese medicinal compound Tianma. Gastrodin can penetrate through the blood-brain barrier and has been suggested to have neuroprotective effects against hypoxia. It is also known to reduce the immunoreactivity of γ-aminobutyric acid shunt enzymes in hippocampal tissues.
Biochem/physiol Actions
Gastrodin is a key bioactive component. The study shows that its clinical application is widely distributed in the treatment of neurasthenia, dizziness, epilepsy, migraine, headache and dementia. Its pharmacological impacts has also been reported in cardiovascular diseases and neointima formation.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
监管及禁止进口产品
此项目有
Ji-Nan Dai et al.
PloS one, 6(7), e21891-e21891 (2011-07-19)
Microglial activation plays an important role in neurodegenerative diseases by producing several proinflammatory enzymes and proinflammatory cytokines. The phenolic glucoside gastrodin, a main constituent of a Chinese herbal medicine, has been known to display anti-inflammatory properties. The current study investigates
Lihua Zhu et al.
International journal of molecular medicine, 30(5), 1034-1040 (2012-08-28)
Vascular smooth muscle cell (VSMC) proliferation plays a critical role in the development of vascular diseases. In the present study, we tested the efficacy and the mechanisms of action of gastrodin, a bioactive component of the Chinese herb Gastrodia elata
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