SMB00701
芝麻林素
≥97%, from Sesamum indicum (sesame)
别名:
5-[(1S,3aR,4R,6aR)-4-（1,3- 苯并二唑-5-烷氧基）四羟基-1H,3H-furo[3,4-c]呋喃-1-基]-1,3-苯并二恶唑
产品名称
芝麻林素, ≥97%, from Sesamum indicum (sesame)
InChI
1S/C20H18O7/c1-3-15-17(25-9-23-15)5-11(1)19-13-7-22-20(14(13)8-21-19)27-12-2-4-16-18(6-12)26-10-24-16/h1-6,13-14,19-20H,7-10H2/t13-,14-,19+,20+/m0/s1
InChI key
ZZMNWJVJUKMZJY-AFHBHXEDSA-N
SMILES string
[H][C@@]12[C@@H](C(C=C3)=CC4=C3OCO4)OC[C@]1([H])[C@@H](OC5=CC6=C(C=C5)OCO6)OC2
biological source
Sesamum indicum (sesame)
assay
≥97%
form
powder
solubility
DMSO: 10 mg/mL
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
Quality Level
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General description
芝麻素是从芝麻中提取的呋喃木脂素。它在水中的溶解度很小。芝麻素的化学结构包括两种苯丙素，它们的丙基侧连接到中心碳上。在许多其他芝麻品种中也有报道。
Biochem/physiol Actions
它还具有抗菌、抗黑色素生成和神经保护作用。
据报道，芝麻素具有有益的生理特性，如抗氧化、抗突变、抗衰老和抗炎活性。 对大鼠肝、肾的脂质过氧化也有抑制作用。芝麻素通过增加Burkitts淋巴瘤细胞上NKG2D配体的表达，增强NK细胞的裂解活性，在癌症治疗中具有潜在的免疫治疗价值。 此外，研究表明，芝麻素可抑制β-分泌酶，通过日常食用对预防痴呆具有重要作用。
signalword
Warning
hcodes
pcodes
Hazard Classifications
Skin Sens. 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Jeong Hwa Kim et al.
International immunopharmacology, 28(2), 977-984 (2015-08-25)
Sesamolin and sesamin are representative lignans found in sesame seed. The present study was designed to demonstrate the anti-cancer activity of sesamolin achieved by increasing the expression level of NKG2D ligands on Raji cells, which are derived from Burkitt's lymphoma.
T Lind et al.
Acta orthopaedica Belgica, 58(1), 81-83 (1992-01-01)
The intra-articular pressures in the glenohumeral joint in different positions were measured in 12 cadaveric shoulders. The lowest pressure was found in abduction combined with traction. A significant rise in pressure was seen in positions combining flexion or abduction with
Reny Rosalina et al.
Molecules (Basel, Switzerland), 26(19) (2021-10-14)
Sesame seeds are rich in lignan content and have been well-known for their health benefits. Unlike the other sesame lignan compounds (i.e., sesamin and sesamol), the study of the pharmacological activity of sesamolin has not been explored widely. This review
M H Kang et al.
The Journal of nutrition, 128(6), 1018-1022 (1998-06-18)
Although the sesame lignans, sesaminol and sesamolinol, have been shown to possess antioxidative activity, less is known about the metabolism and antioxidative properties of sesamolin, a major constituent of sesame oil. To determine the ability of sesamolin to act as
Afaf Kamal-Eldin et al.
Recent patents on food, nutrition & agriculture, 3(1), 17-29 (2010-12-01)
Sesame seed contains very high levels (up to 2.5%) of furofuran lignans with beneficial physiological activities, mainly sesamin, sesamolin, and sesaminol glucosides. Reported activities of sesame seed lignans include inter alias modulation of fatty acid metabolism, inhibition of cholesterol absorption
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