SMB00914
Isovanillic Acid 3-Sulfate Disodium Salt
≥96% (HPLC)
别名:
Isovanillic acid 3-sulfate disodium salt
SMILES string
COC(C=C1)=C(OS(=O)(O[Na])=O)C=C1C(O[Na])=O
assay
≥96% (HPLC)
form
powder
color
, White to off-white
solubility
water: 40 mg/mL
storage temp.
2-8°C
Quality Level
General description
Isovanillic acid 3-O-sulfate (IVAS) is a gut microbial phenolic metabolite primarily derived from consumed cyanidin 3-O-glucoside, a major compound in berry fruits. IVAS is the most effective among the gut microbial phenolic metabolites tested to enhance glucose uptake & metabolism in human skeletal muscle myoblast LHCN-M2. IIVAS is shown to increase glucose transport via GLUT4- and PI3K-dependent mechanisms. IVAS also upregulates GLUT1, GLUT4, PI3K p85a protein level, and Akt phosphorylation, establishing a novel link between gut microbiota, host diet and skeletal muscle energy source utilization.Also another study shows that IVAS restores glycosaminoglycans (GAGs) level and reduce inflammatory markers in diabetic human aortic endothelial cells (HAECs).
Other Notes
For additional information on our range of Biochemicals, please complete this form.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持