SMILES string
O1[C@H]([C@@H](c4c1c(ccc4\C=C\C(=O)O[C@H](Cc5cc(c(cc5)O)O)C(=O)O)O)C(=O)O[C@H](Cc3cc(c(cc3)O)O)C(=O)O)c2cc(c(cc2)O)O
InChI
1S/C36H30O16/c37-20-6-1-16(11-24(20)41)13-27(34(45)46)50-29(44)10-5-18-3-9-23(40)33-30(18)31(32(52-33)19-4-8-22(39)26(43)15-19)36(49)51-28(35(47)48)14-17-2-7-21(38)25(42)12-17/h1-12,15,27-28,31-32,37-43H,13-14H2,(H,45,46)(H,47,48)/b10-5+/t27-,28-,31-,32+/m1/s1
InChI key
SNKFFCBZYFGCQN-PDVBOLEISA-N
biological source
plant
assay
≥85% (LC/MS-ELSD)
form
solid
mol wt
718.61
color
light yellow to brown
solubility
water: soluble
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
General description
Salvianolic acid B, also known as Lithospermic acid B, is a polyphenol and a member of catechols. This bioactive natural compound is commonly found in plants such as Salvia Sp., Isodon rubescens, Mentha Sp., Canna indica, and Angelica keiskei. Existing research suggests that this plant-derived natural product possesses a range of biological properties, including anticancer, anti-inflammatory, hepatoprotective, cardioprotective and neuroprotective activities.
Application
It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.
Biochem/physiol Actions
According to the existing research, Salvianolic acid B plays potential role in modulating inflammation, cell signaling, and immune responses by inhibiting the expression of COX, ERK, TNF-α, NO.
Salvianolic acid B has anti-obesity, antiviral (COVID-19) and free radical scavenging activity.
Features and Benefits
- High quality compound suitable for multiple research applications
- Compatible with HPLC and mass spectrometry techniques
Other Notes
For additional information on our range of Biochemicals, please complete this form.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Lin Li et al.
Food & function, 11(10), 8743-8756 (2020-09-22)
Salvianolic acid B (Sal B) exhibits anti-obesity activity, yet the underlying mechanism linking this effect to metabolic endotoxemia remains unexplored. For this purpose, high-fat diet-induced obese mice were orally administered with Sal B for 10 weeks. Hematoxylin/eosin staining, transmission electron
Repurposing approved drugs as potential inhibitors of 3CL-protease of SARS-CoV-2: Virtual screening and structure based drug design
Almes F J, et al.
Computational Biology and Chemistry, 88, 107351-107351 (2020)
Annarita Viggiano et al.
Applied and environmental microbiology, 84(4) (2017-12-03)
Chrysogine is a yellow pigment produced by Penicillium chrysogenum and other filamentous fungi. Although the pigment was first isolated in 1973, its biosynthetic pathway has so far not been resolved. Here, we show that deletion of the highly expressed nonribosomal
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