SMB01019
Amorfrutin A
≥90% (LC/MS-ELSD)
别名:
2-hydroxy-4-methoxy-3-(3-methylbut-2-enyl)-6-(2-phenylethyl)benzoic acid, 3-hydroxy-4-isopentenyl-5-methoxybibenzyl-2-carboxylic acid
登录 查看组织和合同定价。
选择尺寸
关于此项目
经验公式（希尔记法）:
C21H24O4
化学文摘社编号:
分子量:
340.41
UNSPSC Code:
12352205
NACRES:
NA.25
MDL number:
SMILES string
O(C)c1c(c(c(c(c1)CCc2ccccc2)C(=O)O)O)CC=C(C)C
InChI
1S/C21H24O4/c1-14(2)9-12-17-18(25-3)13-16(19(20(17)22)21(23)24)11-10-15-7-5-4-6-8-15/h4-9,13,22H,10-12H2,1-3H3,(H,23,24)
InChI key
CTNFTPUIYFUXBE-UHFFFAOYSA-N
biological source
plant
assay
≥90% (LC/MS-ELSD)
form
solid
mol wt
340.41
solubility
water: slightly soluble
application(s)
metabolomics
vitamins, nutraceuticals, and natural products
storage temp.
−20°C
General description
Amorfrutin A is a stilbenoid compound commonly present in plants like Glycyrrhiza foetida, Glycyrrhiza acanthocarpa, Cajanus cajan, and Amorpha fruticosa. Current research indicates that this naturally occurring metabolite possesses diverse biological activities, including anti-inflammatory, anticancer, antidiabetic, and antimicrobial properties.
Application
It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.
Biochem/physiol Actions
According to the existing research, Amorfrutin-A demonstrated its ability to inhibit NF-κB activity, a pivotal regulator of genes governing a wide range of cellular functions, such as immune responses, apoptosis, tumor growth, and tissue development. Furthermore, it exhibits anti-inflammatory properties in colon cells by interacting with the nuclear receptor PPARγ, resulting in the reduced expression and secretion of inflammatory mediators. This suggests its potential for treating conditions like inflammatory bowel diseases. Additionally, it also exhibited antidiabetic activity through binding to and activating the nuclear receptor PPARγ.
Features and Benefits
- High quality compound suitable for multiple research applications
- Compatible with HPLC and mass spectrometry techniques
Other Notes
For additional information on our range of Biochemicals, please complete this form.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Amorfrutins are potent antidiabetic dietary natural products
Weidner C, et al.
Proceedings of the National Academy of Sciences of the USA, 109, 7257-7262 (2012)
Amorfrutins Are Natural PPAR? Agonists with Potent Anti-inflammatory Properties
Fuhr L, et al.
Journal of Natural Products, 78, 1160-1164 (2015)
Nguyen Tien Dat et al.
Journal of natural products, 71(10), 1696-1700 (2008-10-10)
NF-kappaB is known to play a crucial role in the regulation of genes controlling the immune system, apoptosis, tumor cell growth, and tissue differentiation. Bioassay-guided fractionation of the n-hexane-soluble fraction of a methanol extract of Amorpha fruticosa afforded four new
我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.
联系客户支持