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Merck
CN

SMB01027

Pomiferin

≥90% (LC/MS-ELSD)

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关于此项目

经验公式(希尔记法):
C25H24O6
化学文摘社编号:
分子量:
420.45
UNSPSC Code:
12352205
NACRES:
NA.25
MDL number:
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biological source

plant

assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

420.45

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

[o]1c2c([c](c(c1)c4cc(c(cc4)O)O)=O)c(c(c3c2C=CC(O3)(C)C)CC=C(C)C)O

InChI

1S/C25H24O6/c1-13(2)5-7-15-21(28)20-22(29)17(14-6-8-18(26)19(27)11-14)12-30-24(20)16-9-10-25(3,4)31-23(15)16/h5-6,8-12,26-28H,7H2,1-4H3

InChI key

GHCZYXUOYFOXIP-UHFFFAOYSA-N

General description

Pomiferin is a prenylated flavonoid and a bioactive natural compound commonly derived from plants such as Citrus aurantium, Derris montana, Maclura pomifera, and Acacia horrida. Current research indicates that this metabolite is an inhibitor and may possess diverse biological activities, including antimicrobial, anticancer, antioxidant, anti-inflammatory, and neuroprotective properties.

Application

Pomiferin is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Pomiferin acts as an potential inhibitor of HDAC, with an IC50 of 1.05 μM, and also potently inhibits mTOR (IC50, 6.2 μM). Pomiferin shows cytotoxic effects on human tumor cell lines. Pomiferin also increases SOD activities and total antioxidative capacity, and decreases malondialdehyde in rats.

Features and Benefits

  • Suitable for Biochemical and Biomedical research
  • Versatile and adaptable for wide variety of laboratory and research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.


存储类别

11 - Combustible Solids

怎么回事?

WGK 3

闪点 (F)

Not applicable

闪点 (°C)

Not applicable



历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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