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Merck
CN

SMB01030

Theviridoside

≥90% (LC/MS-ELSD)

别名:

Methyl (1S,4aR,7aR)-1-(β-D-glucopyranosyloxy)-1,4a,5,7a-tetrahydro-4a-hydroxy-7-(hydroxymethyl)cyclopenta[c]pyran-4-carboxylate (ACI), Theveridoside, Theveside methyl ester

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关于此项目

经验公式(希尔记法):
C17H24O11
化学文摘社编号:
分子量:
404.37
UNSPSC Code:
12352205
NACRES:
NA.25
MDL number:
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SMILES string

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)O[C@@H]2OC=C([C@@]3([C@H]2C(=CC3)CO)O)C(=O)OC

InChI

1S/C17H24O11/c1-25-14(23)8-6-26-15(10-7(4-18)2-3-17(8,10)24)28-16-13(22)12(21)11(20)9(5-19)27-16/h2,6,9-13,15-16,18-22,24H,3-5H2,1H3/t9-,10+,11-,12+,13-,15+,16+,17+/m1/s1

InChI key

LDBMLOLBWUOZGG-DOFVRBEMSA-N

biological source

plant

assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

404.37

solubility

water: soluble

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

General description

Theviridoside, an iridoid glycoside, is a natural product commonly found in plants of Cerbera odollam, Lippia javanica, Lippia turbinata and Thevetia neriifolia. In Cancer research, it exerts a significant effect on cell function and signal transduction, inducing cell cycle arrest and apoptosis in cancer cells while inhibiting the production of pro-inflammatory cytokines. This compound exhibits potent biological activity, including anti-cancer, antifungal, anti-inflammatory, and anti-viral activities.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Theviridoside acts by inhibiting the Na+/K+-ATPase pump, leading to increased intracellular calcium levels and the activation of multiple signaling pathways.

Features and Benefits

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

Lot/Batch Number

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Frédéric Martin et al.
Phytochemistry, 68(9), 1307-1311 (2007-03-27)
Sixteen crude extracts from six Panamanian plants of the family Bignoniaceae were submitted to rapid TLC tests against DPPH and acetylcholinesterase. Pithecoctenium crucigerum (L.) A.H. Gentry, which showed interesting activity against DPPH, has been studied. The chemical investigation of the

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