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Merck
CN

SMB01042

Allocryptopin

≥90% (LC/MS-ELSD)

别名:

β-Allocryptopine, γ-Homochelidonine, Fagarine I

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经验公式(希尔记法):
C21H23NO5
化学文摘社编号:
分子量:
369.41
UNSPSC Code:
12352205
NACRES:
NA.25
MDL number:
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SMILES string

N1(CCc2c(cc4c(c2)OCO4)C(=O)Cc3c(c(c(cc3)OC)OC)C1)C

InChI

1S/C21H23NO5/c1-22-7-6-14-9-19-20(27-12-26-19)10-15(14)17(23)8-13-4-5-18(24-2)21(25-3)16(13)11-22/h4-5,9-10H,6-8,11-12H2,1-3H3

InChI key

HYBRYAPKQCZIAE-UHFFFAOYSA-N

biological source

plant

assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

369.41

solubility

water: slightly soluble

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

General description

Allocryptopin, an isoquinoline alkaliod, is a natural product commonly available from Allocryptopinus japonicus, Glaucium arabicum, Zanthoxylum beecheyanum, Berberis integerrima, and Macleaya cordata. This secondary metabolite derived from plant sources exhibits various biological activities such as anti-inflammatory, antiviral, and antitumor properties.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Allocryptopine has been reported to possess strong antibacterial, anti-inflammatoty, antiparasitic, antineoplastic and anti-addictive activities. Allocryptopine inhibits human acetylcholinesterase and butyrylcholinesterase. It blocks hERG current in HEK293 cells. Allocryptopine strongly enhanced the I(peak) of the T353I channel by enhancing the plasma membrane (PM) expression of Nav1.5 and rescued defective trafficking after co-incubation with HEK293 cells that carry mutation channel 24 h.

Features and Benefits

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

存储类别

11 - Combustible Solids

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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