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Merck
CN

SMB01061

Emetine

≥90% (LC/MS-ELSD)

别名:

(-)-Emetine

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关于此项目

经验公式(希尔记法):
C29H40N2O4
化学文摘社编号:
分子量:
480.64
UNSPSC Code:
12352205
NACRES:
NA.25
MDL number:
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SMILES string

N21[C@@H](C[C@@H]([C@H](C2)CC)C[C@H]4NCCc5c4cc(c(c5)OC)OC)c3c(cc(c(c3)OC)OC)CC1

InChI

1S/C29H40N2O4/c1-6-18-17-31-10-8-20-14-27(33-3)29(35-5)16-23(20)25(31)12-21(18)11-24-22-15-28(34-4)26(32-2)13-19(22)7-9-30-24/h13-16,18,21,24-25,30H,6-12,17H2,1-5H3/t18-,21-,24+,25-/m0/s1

InChI key

AUVVAXYIELKVAI-CKBKHPSWSA-N

biological source

plant

assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

480.64

solubility

water: soluble

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

General description

Emetine, a pyridoisoquinoline alkaloid, is a bioactive natural compound commonly derived from plants such as Helichrysum revolutum, Sphaerophysa salsula, Coryphantha elephantidens, Uragoga ipecacuanha, Uragoga acuminata and Clonostachys rosea. Current research suggests that this metabolite acts as an inhibitor and may exhibit diverse biological activities, including antiprotozoal, antitumor, anti-inflammatory, anti-infective, antimalarial, and antiviral properties.

Application

Emetine is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and drug discovery research.

Biochem/physiol Actions

Emetine is the principal pyridoisoquinoline of ipecac, from the ground roots of Uragoga (or Cephaelis) ipecacuanha or U. acuminata, of the Rubiaceae.
Emetine is used as an amebicide in many different preparations and may cause serious cardiac, hepatic, or renal damage and violent diarrhea and vomiting. Emetine inhibits protein synthesis in eukaryotic cells but not prokaryotic cells.

Features and Benefits

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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