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Merck
CN

SMB01064

Dimethylfraxetin

≥90% (LC/MS-ELSD)

别名:

6,7,8,-trimethoxycoumarin, 6,7,8-trimethoxychromen-2-one, Fraxidin Methyl Ether

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关于此项目

经验公式(希尔记法):
C12H12O5
化学文摘社编号:
分子量:
236.22
UNSPSC Code:
12352205
NACRES:
NA.25
MDL number:
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SMILES string

[o]1c2c(cc[c]1=O)cc(c(c2OC)OC)OC

InChI

1S/C12H12O5/c1-14-8-6-7-4-5-9(13)17-10(7)12(16-3)11(8)15-2/h4-6H,1-3H3

InChI key

RAYQKHLZHPFYEJ-UHFFFAOYSA-N

biological source

plant

assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

236.22

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

General description

Dimethylfraxetin, also known as 6,7,8-Trimethoxycoumarin, a coumarin derivative, is a natural product commonly found in Pittosporum illicioides, Garcinia multiflora, and Cryptocarya bracteolata. It exhibits a range of biological activities, including anti-inflammatory, antioxidant, anticancer, and antimicrobial properties.

Application

It is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical and biochemical research.

Biochem/physiol Actions

  • Binds to the CB2 receptor and induces immunomodulatory effects.
  • Exhibits anti-inflammatory properties by inhibiting prostaglandin synthesis in the human erythroleukemia cell line K562.
  • Inhibits the replication of both DNA and RNA.
  • Blocks aminoacyl-tRNA binding to ribosomes, inhibiting protein synthesis.
  • Binds to phenolic acid receptors on cultured cells.

Features and Benefits

  • High quality compound suitable for multiple research applications
  • Compatible with HPLC and mass spectrometry techniques

Other Notes

For additional information on our range of Biochemicals, please complete this form.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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