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Merck
CN

SMB01070

Cirsimarin

≥90% (LC/MS-ELSD)

别名:

5,4′-Dihydroxy-6,7-dimethoxyflavone 4′-O-β-D-glucoside, Cirsimaretin, Cirsimaritin 4′-glucoside, Cirsitakaoside

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关于此项目

经验公式(希尔记法):
C23H24O11
化学文摘社编号:
分子量:
476.43
UNSPSC Code:
12352205
NACRES:
NA.25
MDL number:
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biological source

plant

assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

476.43

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

SMILES string

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1CO)O)O)O)Oc2ccc(cc2)c3[o]c4c([c](c3)=O)c(c(c(c4)OC)OC)O

InChI

1S/C23H24O11/c1-30-15-8-14-17(19(27)22(15)31-2)12(25)7-13(33-14)10-3-5-11(6-4-10)32-23-21(29)20(28)18(26)16(9-24)34-23/h3-8,16,18,20-21,23-24,26-29H,9H2,1-2H3/t16-,18-,20+,21-,23-/m1/s1

InChI key

RETJLKUBHXTIGH-FZFRBNDOSA-N

General description

Cirsimarin is an antilipogenic flavonoid compound commonly found in plants such as Cirsium japonicum, Scoparia dulcis, Cirsium rhinoceros, and Microtea debilis. Recent research suggests that this naturally occurring metabolite may possess a wide range of biological activities, including cytoprotective, anti-inflammatory, antioxidant, antiviral, antiadipogenic, and antimicrobial properties.

Application

Cirsimarin is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Cirsimarin exerts potent antilipogenic effect and decreases adipose tissue deposition in mice. Cirsimarin could therefore be a potential candidate for the treatment of obesity.

Features and Benefits

  • Suitable for Biochemical and Biomedical research
  • Versatile and adaptable for wide variety of laboratory and research applications

Other Notes

For additional information on our range of Biochemicals, please complete this form.


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存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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B Zarrouki et al.
International journal of obesity (2005), 34(11), 1566-1575 (2010-05-12)
We previously reported that the flavonoid cirsimarin exerts in vitro a strong lipolytic activity on isolated adipocytes. This study was therefore designed to evaluate in vivo the effects of cirsimarin on white adipose tissue (WAT) accretion in mice. Male CD1