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Merck
CN

SMB01073

Eurycomanone

≥90% (LC/MS-ELSD)

别名:

Pasakbumin A

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关于此项目

经验公式(希尔记法):
C20H24O9
化学文摘社编号:
分子量:
408.40
UNSPSC Code:
12352205
NACRES:
NA.25
MDL number:
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产品名称

Eurycomanone, ≥90% (LC/MS-ELSD)

SMILES string

O1[C@@]2([C@H]3[C@]4([C@H](OC(=O)[C@@H]([C@]4(C(=C)[C@H]2O)O)O)C[C@@H]5[C@@]3([C@@H](C(=O)C=C5C)O)C)C1)O

InChI

1S/C20H24O9/c1-7-4-10(21)13(23)17(3)9(7)5-11-18-6-28-20(27,16(17)18)12(22)8(2)19(18,26)14(24)15(25)29-11/h4,9,11-14,16,22-24,26-27H,2,5-6H2,1,3H3/t9-,11+,12+,13+,14-,16+,17+,18+,19-,20-/m0/s1

InChI key

UCUWZJWAQQRCOR-OKNZMGBLSA-N

biological source

plant

assay

≥90% (LC/MS-ELSD)

form

solid

mol wt

408.4

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

−20°C

Application

Eurycomanone is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Biochem/physiol Actions

Eurycomanone inhibited Jurkat and K562 leukemia cells viability and proliferation without affecting healthy cells and enhanced testosterone steroidogenesis.

Features and Benefits

  • Suitable for Biochemical and Biomedical research
  • Versatile and adaptable for wide variety of laboratory and research applications

General description

Eurycomanone, also known as Pasakbumin A, is a bioactive quassinoid natural compound commonly derived from Eurycoma longifolia (Tongkat Ali). Current research indicates that this plant metabolite is an inhibitor and may possess diverse biological activities, including antitumor, antimalarial, and anticancer properties.

Other Notes

For additional information on our range of Biochemicals, please complete this form.

pictograms

Exclamation mark

signalword

Warning

hcodes

Hazard Classifications

Acute Tox. 4 Oral

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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Shéhérazade Hajjouli et al.
Molecules (Basel, Switzerland), 19(9), 14649-14666 (2014-09-18)
Eurycomanone and eurycomanol are two quassinoids from the roots of Eurycoma longifolia Jack. The aim of this study was to assess the bioactivity of these compounds in Jurkat and K562 human leukemia cell models compared to peripheral blood mononuclear cells
Bin-Seng Low et al.
Journal of ethnopharmacology, 149(1), 201-207 (2013-07-03)
Eurycoma longifolia Jack (Simaroubaceae family), known locally as 'Tongkat Ali' by the ethnic population, is popularly taken as a traditional remedy to improve the male libido, sexual prowess and fertility. Presently, many tea, coffee and carbonated beverages, pre-mixed with the

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