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Merck
CN

SML0014

Scutellarin hydrate

≥98% (HPLC)

别名:

7-(β-D-Glucopyranuronosyloxy)-5,6-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one hydrate, Breviscapin, Scutellarein-7-O-β-D-glucuronide, 5,6-Dihydroxy-2-(4-hydroxyphenyl)-4-oxo-4H-1-benzopyran-7-yl-β-D-glucopyranosiduronic acid hydrate

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关于此项目

经验公式（希尔记法）:
C21H18O12 · xH2O
化学文摘社编号:
27740-01-8
分子量:
462.36 (anhydrous basis)
UNSPSC Code:
12352200
NACRES:
NA.77

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SMILES string

O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1C(=O)O)O)O)O)Oc2cc3c(c(c2O)O)C(=O)C=C(O3)c4ccc(cc4)O

InChI key

DJSISFGPUUYILV-ZFORQUDYSA-N

InChI

1S/C21H18O12/c22-8-3-1-7(2-4-8)10-5-9(23)13-11(31-10)6-12(14(24)15(13)25)32-21-18(28)16(26)17(27)19(33-21)20(29)30/h1-6,16-19,21-22,24-28H,(H,29,30)/t16-,17-,18+,19-,21+/m0/s1

assay

≥98% (HPLC)

form

powder

storage condition

desiccated

color

yellow

solubility

DMSO: ≥10 mg/mL

storage temp.

2-8°C

Quality Level

100

Application

Scutellarin hydrate may be used in MAPK-mediated cell signaling studies.

Biochem/physiol Actions

Scutellarin is a flavonoid that exhibits a number of cardio- and neuro-protective effects. Scutellarin inhibits p38 activity, ERK phosphorylation, and TGF-β expression and fibrosis in a rat myocardial infarct model. In a cerebral ischemia-reperfusion model, the compound reduced infarct volume and neurological deficits by increasing eNOS expression while inhibiting the induction of iNOS.

Features and Benefits

This compound is featured on the MAPKs and Nitric Oxide Synthases pages of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000169320
0000169320
0000137119
0000137117
0000059766

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