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Merck
CN

SML0032

三乙酰白藜芦醇

≥98% (HPLC)

别名:

3,5,4′-Tri-O-acetylresveratrol, 5-[(1E)-2-[4-(acetyloxy)phenyl]ethenyl]-1,3-Benzenediol-1,3-diacetate

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关于此项目

经验公式(希尔记法):
C20H18O6
化学文摘社编号:
分子量:
354.35
NACRES:
NA.25
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
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产品名称

三乙酰白藜芦醇, ≥98% (HPLC)

InChI

1S/C20H18O6/c1-13(21)24-18-8-6-16(7-9-18)4-5-17-10-19(25-14(2)22)12-20(11-17)26-15(3)23/h4-12H,1-3H3/b5-4+

SMILES string

CC(=O)Oc1ccc(cc1)\C=C\c2cc(OC(C)=O)cc(OC(C)=O)c2

InChI key

PDAYUJSOJIMKIS-SNAWJCMRSA-N

assay

≥98% (HPLC)

form

powder

storage condition

protect from light

color

white to tan

solubility

DMSO: ≥18 mg/mL

application(s)

metabolomics
vitamins, nutraceuticals, and natural products

storage temp.

room temp

Quality Level

Biochem/physiol Actions

Resveratrol prodrug. SIRT inhibitor
Resveratrol prodrug. SIRT inhibitor
Resveratrol (RSV) plays a protective role on the nervous and cardiovascular systems. It is considered as a modulator of energetic metabolism as it controls glucose homeostasis in obese mice, improves fatty acid oxidation (FAO) and promotes the expression of genes that participate in mitochondrial biogenesis.
Triacetyl resveratrol displays superior bioavailability to the parent compound, resveratrol. The compound induces p53 activity and inhibits proliferation in breast and prostate tumor cell lines.

General description

Resveratrol (RSV) is a natural polyphenolic antioxidant.

存储类别

11 - Combustible Solids

wgk

WGK 3

法规信息

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历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Tammy R Dugas et al.
Journal of biomedical materials research. Part B, Applied biomaterials, 107(3), 646-651 (2018-08-10)
Peripheral artery disease is a cardiovascular disease characterized by a narrowing of arteries that supply blood to the extremities, particularly, the legs. When surgical intervention is warranted, the primary approach is balloon angioplasty. Drug coated balloons (DCB) designed to release
Liqiong Ding et al.
Biochemical pharmacology, 171, 113691-113691 (2019-11-11)
Resveratrol is a natural compound found in many plant species that has broad therapeutic benefits. Here, we investigated the effects of resveratrol on the replication of HSV-2. We found that resveratrol accelerated replication of HSV-2 and increased release of progeny
Resveratrol induces a mitochondrial complex I dependent increase in NADH oxidation responsible for sirtuin activation in liver cells.
Desquiret-Dumas V, et al.
The Journal of Biological Chemistry, 2013 (2013)
Xiaoyun Zeng et al.
Journal of agricultural and food chemistry, 65(22), 4384-4394 (2017-05-05)
The persistence of latent HIV reservoirs presents a significant challenge to viral eradication. Effective latency reversing agents (LRAs) based on "shock and kill" strategy are urgently needed. The natural phytoalexin resveratrol has been demonstrated to enhance HIV gene expression, although
Yoojin Lee et al.
Journal of innate immunity, 13(2), 94-106 (2020-09-17)
Natural killer (NK) cells are innate immune lymphocytes that play an important role in anti-viral and anti-tumour immune responses. Several cancer immunotherapy approaches targeting NK cells are currently in clinical or preclinical development. Here, we aimed to find food nutrients

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