SML0054
五味子醇甲
≥98% (HPLC), Antioxidant, powder
别名:
(+)-五味子乙素, 五味子碱, 五味子素, 五味子醇 A, 五味子醇甲
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关于此项目
经验公式（希尔记法）:
C24H32O7
化学文摘社编号:
分子量:
432.51
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
MDL number:
产品名称
五味子醇甲, ≥98% (HPLC)
SMILES string
COc1cc2C[C@H](C)[C@@](C)(O)Cc3cc(OC)c(OC)c(OC)c3-c2c(OC)c1OC
InChI
1S/C24H32O7/c1-13-9-14-10-16(26-3)20(28-5)22(30-7)18(14)19-15(12-24(13,2)25)11-17(27-4)21(29-6)23(19)31-8/h10-11,13,25H,9,12H2,1-8H3/t13-,24-/m0/s1
InChI key
YEFOAORQXAOVJQ-RZFZLAGVSA-N
assay
≥98% (HPLC)
form
powder
optical activity
[α]/D 75 to 95°, c = 1 in methanol
color
white to beige
solubility
DMSO: ≥13 mg/mL
storage temp.
room temp
Quality Level
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Application
五味子甲素可用于氧化应激相关的细胞信号传导研究。
Biochem/physiol Actions
五味子甲素是一种天然产物，具有抗氧化和抗炎作用。减少 ROS 的形成，抑制线粒体途径的凋亡过程和氧化应激。据报道，五味子甲素具有保肝、抗肿瘤、抗病毒、抗遗忘作用，对谷氨酸引起的神经毒性具有神经保护活性。
抗氧化剂；抗炎，减少氧化应激。
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Shih-Hung Yang et al.
Journal of the science of food and agriculture, 91(4), 694-702 (2011-02-09)
Schisandra chinensis, commonly used in Asia for tea material and traditional Chinese medicine, is presumed to enhance mental and intellectual functions. In this study, the effects and signalling mechanisms of a purified compound schisandrin, one of the lignan of Schisandra
Sun Young Park et al.
Immunology letters, 139(1-2), 93-101 (2011-06-08)
The lipopolysaccharide (LPS) of Porphyromonas gingivalis is thought to induce periodontitis. In this study, we isolated Schisandrin from the dried fruits of Schisandra chinensis and examined the anti-inflammatory effect of Schisandrin in macrophages stimulated with LPS from P. gingivalis. First
Bing Shao et al.
Drug development and industrial pharmacy, 36(11), 1356-1363 (2010-09-21)
Wurenchun is the alcohol extract from Fructus Schisandrae Chinensis, which has good efficiency in lowering abnormal serum glutamic pyruvic transaminase (SGPT) level of patients suffering from acute or chronic hepatitis. The main purpose of this work is to prepare self-emulsifying
Si-Yuan Pan et al.
Lipids in health and disease, 11, 120-120 (2012-09-20)
Schisandra, a globally distributed plant, has been widely applied to health care products. Here, we investigated the effects of dietary intake of Fructus Schisandrae chinensis (FSC), both aqueous and ethanolic extracts (AqFSC, EtFSC), on serum/hepatic lipid contents in normal diet
Jia-Ming Yang et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(13), 1153-1160 (2011-07-19)
In this study, the herbal extracts of Schisandra chinensis were demonstrated to inhibit the contractions induced by acetylcholine (ACh) and serotonin (5-HT) in guinea pig ileum, and the 95% ethanol extract was more effective than the aqueous extract. Analysis with
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