SML0054
五味子醇甲
≥98% (HPLC), Antioxidant, powder
别名:
(+)-五味子乙素, 五味子碱, 五味子素, 五味子醇 A, 五味子醇甲
Product Name
五味子醇甲, ≥98% (HPLC)
质量水平
方案
≥98% (HPLC)
表单
powder
旋光性
[α]/D 75 to 95°, c = 1 in methanol
颜色
white to beige
溶解性
DMSO: ≥13 mg/mL
储存温度
room temp
SMILES字符串
COc1cc2C[C@H](C)[C@@](C)(O)Cc3cc(OC)c(OC)c(OC)c3-c2c(OC)c1OC
InChI
1S/C24H32O7/c1-13-9-14-10-16(26-3)20(28-5)22(30-7)18(14)19-15(12-24(13,2)25)11-17(27-4)21(29-6)23(19)31-8/h10-11,13,25H,9,12H2,1-8H3/t13-,24-/m0/s1
InChI key
YEFOAORQXAOVJQ-RZFZLAGVSA-N
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应用
五味子甲素可用于氧化应激相关的细胞信号传导研究。
生化/生理作用
五味子甲素是一种天然产物,具有抗氧化和抗炎作用。减少 ROS 的形成,抑制线粒体途径的凋亡过程和氧化应激。据报道,五味子甲素具有保肝、抗肿瘤、抗病毒、抗遗忘作用,对谷氨酸引起的神经毒性具有神经保护活性。
抗氧化剂;抗炎,减少氧化应激。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
历史批次信息供参考:
分析证书(COA)
Lot/Batch Number
Jiaming Yang et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(11), 998-1005 (2011-04-26)
This study examined the effect of schisandrin, one of the major lignans isolated from Schisandra chinensis, on spontaneous contraction in rat colon and its possible mechanisms. Schisandrin produced a concentration-dependent inhibition (EC₅₀=1.66 μM) on the colonic spontaneous contraction. The relaxant
Chun-hui Ma et al.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 879(30), 3444-3451 (2011-10-04)
In this study, ester-bond biphenyl cyclooctene lignans were efficiently hydrolytically degraded into free biphenyl cyclooctene lignans by ion exchange resin transformation and simultaneous removal of impurities by macroporous resin. The OH-type strongly basic anion exchange resin 201×7 was the best
Chun-hui Ma et al.
Analytica chimica acta, 689(1), 110-116 (2011-02-23)
The ionic liquid-based ultrasonic-assisted extraction (ILUAE) has been successfully applied in extracting four biphenyl cyclooctene lignans from the fruit of Schisandra chinensis Baill. Seventeen different types of ionic liquids with different cations and anions have been investigated. 0.8 M 1-lauryl-3-methylimidazolium
Di Hu et al.
Oxidative medicine and cellular longevity, 2012, 721721-721721 (2012-07-26)
In the present study, we examined the effect of schisandrin (SCH) of Schisandra chinensis on the amyloid-beta(1-42)- (Aβ(1-42)-) induced memory impairment in mice and elucidated the possible antioxidative mechanism. Mice were intracerebroventricular (i.c.v.) injected with the aggregated Aβ(1-42) and then
Ju-Xian Song et al.
Phytotherapy research : PTR, 25(3), 435-443 (2010-08-27)
Aggregated beta-amyloid (Aβ) and elevated plasma levels of homocysteine have been implicated as critical factors in the pathogenesis of Alzheimer's disease. The neuroprotective effects and possible mechanism of four structurally similar dibenzocyclooctadiene lignans (namely schisandrin, schisantherin A, schisandrin B and
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