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Merck
CN

SML0054

Sigma-Aldrich

五味子醇甲

≥98% (HPLC), Antioxidant, powder

别名:

(+)-五味子乙素, 五味子碱, 五味子素, 五味子醇 A, 五味子醇甲

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关于此项目

经验公式(希尔记法):
C24H32O7
化学文摘社编号:
分子量:
432.51
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
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产品名称

五味子醇甲, ≥98% (HPLC)

方案

≥98% (HPLC)

表单

powder

旋光性

[α]/D 75 to 95°, c = 1 in methanol

颜色

white to beige

溶解性

DMSO: ≥13 mg/mL

储存温度

room temp

SMILES字符串

COc1cc2C[C@H](C)[C@@](C)(O)Cc3cc(OC)c(OC)c(OC)c3-c2c(OC)c1OC

InChI

1S/C24H32O7/c1-13-9-14-10-16(26-3)20(28-5)22(30-7)18(14)19-15(12-24(13,2)25)11-17(27-4)21(29-6)23(19)31-8/h10-11,13,25H,9,12H2,1-8H3/t13-,24-/m0/s1

InChI key

YEFOAORQXAOVJQ-RZFZLAGVSA-N

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应用

五味子甲素可用于氧化应激相关的细胞信号传导研究。

生化/生理作用

五味子甲素是一种天然产物,具有抗氧化和抗炎作用。减少 ROS 的形成,抑制线粒体途径的凋亡过程和氧化应激。据报道,五味子甲素具有保肝、抗肿瘤、抗病毒、抗遗忘作用,对谷氨酸引起的神经毒性具有神经保护活性。
抗氧化剂;抗炎,减少氧化应激。

储存分类代码

11 - Combustible Solids

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable


历史批次信息供参考:

分析证书(COA)

Lot/Batch Number

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Phil-Dong Moon et al.
Life sciences, 91(11-12), 384-388 (2012-08-22)
Thymic stromal lymphopoietin (TSLP) plays an important role in allergic diseases such as asthma and atopic dermatitis. Schizandrin has various effects such as anti-asthmatic, anti-cancer and anti-inflammatory effects. However, the effect of schizandrin on the production of TSLP has not
Guangxin Yuan et al.
Molecules (Basel, Switzerland), 16(5), 3713-3722 (2011-05-05)
Lignans are imporant active ingredients of Schisandra sphenanthera. A micellar electrokinetic chromatography method was developed for the simultaneous determination of eight lignans--schizandrin, schisandrol B, schisantherin A, schisanhenol, anwulignan, deoxyschizandrin, schizandrin B and schizandrin C--in different parts of S. sphenanthera. The
Jia-Ming Yang et al.
Phytomedicine : international journal of phytotherapy and phytopharmacology, 18(13), 1153-1160 (2011-07-19)
In this study, the herbal extracts of Schisandra chinensis were demonstrated to inhibit the contractions induced by acetylcholine (ACh) and serotonin (5-HT) in guinea pig ileum, and the 95% ethanol extract was more effective than the aqueous extract. Analysis with
Bing Shao et al.
Drug development and industrial pharmacy, 36(11), 1356-1363 (2010-09-21)
Wurenchun is the alcohol extract from Fructus Schisandrae Chinensis, which has good efficiency in lowering abnormal serum glutamic pyruvic transaminase (SGPT) level of patients suffering from acute or chronic hepatitis. The main purpose of this work is to prepare self-emulsifying
Si-Yuan Pan et al.
Lipids in health and disease, 11, 120-120 (2012-09-20)
Schisandra, a globally distributed plant, has been widely applied to health care products. Here, we investigated the effects of dietary intake of Fructus Schisandrae chinensis (FSC), both aqueous and ethanolic extracts (AqFSC, EtFSC), on serum/hepatic lipid contents in normal diet

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