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安全信息

SML0117

Sigma-Aldrich

磷苯妥英 二钠盐 水合物

≥98% (HPLC)

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别名:
5,5-Diphenyl-3-[(phosphonooxy)methyl]-2,4-imidazolidinedione disodium salt hydrate
经验公式（希尔记法）:
C16H13N2Na2O6P · xH2O
CAS号:
92134-98-0
分子量:
406.24 (anhydrous basis)
MDL编号:
MFCD20527322
PubChem化学物质编号:
329825169

质量水平

100

检测方案

≥98% (HPLC)

形式

powder

颜色

white to tan

溶解性

H2O: ≥15 mg/mL

储存温度

2-8°C

SMILES string

O.[Na+].[Na+].[O-]P([O-])(=O)OCN1C(=O)NC(C1=O)(c2ccccc2)c3ccccc3

InChI

1S/C16H15N2O6P.2Na.H2O/c19-14-16(12-7-3-1-4-8-12,13-9-5-2-6-10-13)17-15(20)18(14)11-24-25(21,22)23;;;/h1-10H,11H2,(H,17,20)(H2,21,22,23);;;1H2/q;2*+1;/p-2

InChI key

WPAVXKKGWCHUAK-UHFFFAOYSA-L

生化/生理作用

Fosphenytoin is a water soluble phenytoin prodrug.

象形图

Exclamation markHealth hazard
GHS07,GHS08

警示用语：

Danger

危险声明

H302 - H350 - H360

危险分类

Acute Tox. 4 Oral - Carc. 1B - Repr. 1B

储存分类代码

6.1C - Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

WGK

WGK 3

闪点(°F)

Not applicable

闪点(°C)

Not applicable

法规信息

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Fatal errors with cerebyx.
Kellie Taylor et al.
Journal of emergency nursing: JEN : official publication of the Emergency Department Nurses Association, 34(5), 460-461 (2008-09-23)
Suzette M LaRoche et al.
Seizure, 20(6), 505-508 (2011-04-05)
Subacute encephalopathy with seizures in chronic alcoholism (SESA) was first described in 1981 by Niedermeyer who reported alcoholic patients presenting with confusion, seizures and focal neurological deficits and is quite distinct from patients presenting with typical alcohol withdrawal seizures. EEG
Amanda M Ranzino et al.
Journal of pharmacy practice, 23(2), 140-143 (2011-04-22)
Thrombocytopenia, defined as a platelet count less than 150 000/µL, occurs as a result of decreased production, sequestration, or peripheral destruction. Drug-induced thrombocytopenia is a clinically important adverse drug event involving many drugs including hydantoins. This report details an acute
Patrick Michael Aaronson et al.
The American journal of emergency medicine, 29(9), 983-988 (2010-08-06)
A comparison of length of stay in an emergency department (ED) after loading patients at risk for seizures with either intravenous (IV) phenytoin or intramuscular (IM) fosphenytoin was studied. This was a retrospective observational cohort study that was conducted over
Sandeep Soni et al.
Pediatric blood & cancer, 59(4), 762-764 (2012-03-02)
Anti-seizure prophylaxis is routinely utilized during busulfan administration for HSCT. We evaluated the feasibility and efficacy of levetiracetam in children undergoing HSCT. A total of 28 children and young adults received levetiracetam during HSCT and the outcomes and costs were
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