The SML0165 ligand was shown to antagonize the activity of the GABA-B agonist, GABA, in a recombinant CHO cell line expressing the human GABA-B1 and GABA-B2 receptors and a serum-responsive secreted placental alkaline phosphatase (SPAP) reporter gene.

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Dissolve 0.2 mg in 21.2 ul of DMSO to give a 10mM stock solution. Once reconstituted into DMSO the product, must be stored, preferably in smaller aliquots, at -20°C.