SML0189
Indinavir sulfate salt hydrate
≥98% (HPLC), powder, antiretroviral agent
别名:
2,3,5-Trideoxy-N-[(1S,2R)-2,3-dihydro-2-hydroxy-1H-inden-1-yl]-5-[(2S)-2-[[(1,1-dimethylethyl)amino]carbonyl]-4-(3-pyridinylmethyl)-1-piperazinyl]-2-(phenylmethyl)-D-erythro-pentonamide sulfate hydrate, Crixivan hydrate, L-735,524 hydrate, MK-639 hydrate
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关于此项目
经验公式（希尔记法）:
C36H47N5O4·H2SO4 · xH2O
分子量:
711.87 (anhydrous basis)
UNSPSC Code:
51111800
NACRES:
NA.77
产品名称
Indinavir sulfate salt hydrate, ≥98% (HPLC)
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to tan
solubility
H2O: ≥15 mg/mL
originator
Merck & Co., Inc., Kenilworth, NJ, U.S.
storage temp.
2-8°C
Quality Level
Application
Indinavir sulfate salt hydrate may be used in HIV-related cell signaling studies.
Biochem/physiol Actions
Indinavir sulfate is an antiretroviral; HIV Protease Inhibitor
Indinavir sulfate is an antiviral HIV protease inhibitor.
Indinavir sulfate suppresses the replication of HIV and is an important component of antiretroviral therapy for initial treatment of HIV infection. It is known to cause renal and urologic toxicity.
Features and Benefits
This compound was developed by Merck & Co., Inc., Kenilworth, NJ, U.S.. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Ryan D Cooper et al.
Nephron. Clinical practice, 118(3), c262-c268 (2011-01-08)
The introduction of potent combination antiretroviral therapy (ART) in the treatment of HIV infection has permitted reliable control of disease progression and has markedly improved survival among people with HIV. As a result, health care providers and patients have shifted
Benjamin Seyer et al.
Journal of neurochemistry, 153(4), 485-494 (2019-09-27)
Ethyl2-acetylamino-7-hydroxy-4-pyridin-3-yl-4H-chromene-3-carboxylate (HFI-419), the benzopyran-based inhibitor of insulin-regulated aminopeptidase (IRAP), has previously been shown to improve spatial working and recognition memory in rodents. However, the mechanism of its cognitive-enhancing effect remains unknown. There is a close correlation between dendritic spine density
商品
Bioactive small molecules for immune system signaling target identification/validation and antibiotics, antivirals, and antifungals offered.
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