SML0214
SAMT-247
≥98% (HPLC)
别名:
3-(S-Acetylthiosalicyloyl)aminopropamide, N-[2-Acetylthiobenzoyl]-β-alaninamide
assay
≥98% (HPLC)
form
powder
color
white to light yellow
solubility
H2O: ≥2 mg/mL at 60 °C
storage temp.
2-8°C
Quality Level
Application
SAMT-247 may be used in HIV-1 related studies.
Biochem/physiol Actions
HIV inhibitor by modifying the NCp7 region of Gag in infected cells
SAMT-247 inhibits HIV by modifying the nucleocapsid NCp7 region of Gag in infected cells, blocking Gag processing and reducing infectivity.
SAMT-247 is a microbicide that decreases the viral infectivity and infectivity of the progeny virus in HIV-1 infections.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Cecilia Cheng-Mayer et al.
AIDS (London, England), 25(15), 1833-1841 (2011-07-14)
Development of an effective vaccine or topical compound to prevent HIV transmission remains a major goal for control of the AIDS pandemic. Using a nonhuman primate model of heterosexual HIV-1 transmission, we tested whether a topical microbicide that reduces viral
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