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Merck
CN

SML0228

Rc-Ome

≥98% (HPLC)

别名:

(2E)-3-(2-hydroxy-5-methoxyphenyl)-1-(4-methoxyphenyl)-2-Propen-1-one, trans-6,4′-dimethoxyretrochalcone

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关于此项目

经验公式(希尔记法):
C17H16O4
化学文摘社编号:
分子量:
284.31
NACRES:
NA.77
UNSPSC Code:
12352202
Assay:
≥98% (HPLC)
Form:
powder
Quality level:
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Quality Level

assay

≥98% (HPLC)

form

powder

color

, light to dark yellow

solubility

DMSO: ≥10 mg/mL

storage temp.

2-8°C

Application

Rc-Ome may be used in GABAA-mediated cell signaling studies.

Biochem/physiol Actions

Rc-OMe is a GABAA PAM
Rc-OMe is a GABAA PAM that distinguishes α1β2γ2s from α1β2 receptors. The compound has very weak potentiating effects on α1β2, but potentiates GABA-elicited currents of α(123)β2γ2s receptors, all with low μM EC50s. Rc-OMe acts at a binding site that is distinct from BDZ, pentobarbital and loreclezole modulatory sites.

Features and Benefits

This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

pictograms

Environment

signalword

Warning

hcodes

Hazard Classifications

Aquatic Acute 1

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

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分析证书(COA)

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全球贸易项目编号

货号GTIN
SML0228-5MG04061832075204
SML0228-25MG04061832260839

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