SML0228
Rc-Ome
≥98% (HPLC)
别名:
(2E)-3-(2-hydroxy-5-methoxyphenyl)-1-(4-methoxyphenyl)-2-Propen-1-one, trans-6,4′-dimethoxyretrochalcone
产品名称
Rc-Ome, ≥98% (HPLC)
assay
≥98% (HPLC)
form
powder
color
, light to dark yellow
solubility
DMSO: ≥10 mg/mL
storage temp.
2-8°C
Quality Level
Application
Rc-Ome may be used in GABAA-mediated cell signaling studies.
Biochem/physiol Actions
Rc-OMe is a GABAA PAM
Rc-OMe is a GABAA PAM that distinguishes α1β2γ2s from α1β2 receptors. The compound has very weak potentiating effects on α1β2, but potentiates GABA-elicited currents of α(123)β2γ2s receptors, all with low μM EC50s. Rc-OMe acts at a binding site that is distinct from BDZ, pentobarbital and loreclezole modulatory sites.
Features and Benefits
This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Warning
hcodes
pcodes
Hazard Classifications
Aquatic Acute 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
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