SML0266
AA 29504
≥98% (HPLC)
别名:
N-[2-Amino-4-[[(2,4,6-trimethylphenyl)methyl]amino]phenyl]-carbamic acid-ethyl ester
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关于此项目
经验公式（希尔记法）:
C19H25N3O2
化学文摘社编号:
分子量:
327.42
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352202
MDL number:
产品名称
AA 29504, ≥98% (HPLC)
InChI key
SCOOTUMXCXKEAD-UHFFFAOYSA-N
SMILES string
CCOC(=O)Nc1ccc(NCc2c(C)cc(C)cc2C)cc1N
InChI
1S/C19H25N3O2/c1-5-24-19(23)22-18-7-6-15(10-17(18)20)21-11-16-13(3)8-12(2)9-14(16)4/h6-10,21H,5,11,20H2,1-4H3,(H,22,23)
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: ≥2 mg/mL
storage temp.
−20°C
Quality Level
Biochem/physiol Actions
AA29504 is a GABAA positive modulator with a preference for extra-synaptic α4β3δ over α1β3γ2s synaptic receptors. AA29504 exhibits anxiolytic effects and reduces motor coordination in rat models.
AA29504 is a GABAA positive modulator.
Features and Benefits
This compound is featured on the GABAA Receptors page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Warning
hcodes
Hazard Classifications
Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Christina B Falk-Petersen et al.
Basic & clinical pharmacology & toxicology, 121(2), 119-129 (2017-03-17)
δ-Containing GABAA receptors are located extrasynaptically and mediate tonic inhibition. Their involvement in brain physiology positions them as interesting drug targets. There is thus a continued interest in establishing reliable recombinant expression systems for δ-containing GABAA receptors. Inconveniently, the recombinant
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