SML0283
盐酸阿莫罗芬 盐酸盐
≥98% (HPLC), Ergosterol biosynthesis inhibitor, powder
别名:
(2R,6S)-rel-4-[3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl]-2,6-dimethyl-morpholine hydrochloride, Ro 14-4767/002
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关于此项目
经验公式（希尔记法）:
C21H35ON · HCl
化学文摘社编号:
分子量:
353.97
UNSPSC Code:
12352200
PubChem Substance ID:
NACRES:
NA.77
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
产品名称
盐酸阿莫罗芬 盐酸盐, ≥98% (HPLC)
Quality Segment
assay
≥98% (HPLC)
form
powder
storage condition
desiccated
color
white to beige
solubility
DMSO: ≥5 mg/mL (warmed)
storage temp.
room temp
SMILES string
Cl.CCC(C)(C)c1ccc(CC(C)CN2C[C@H](C)O[C@H](C)C2)cc1
InChI
1S/C21H35NO.ClH/c1-7-21(5,6)20-10-8-19(9-11-20)12-16(2)13-22-14-17(3)23-18(4)15-22;/h8-11,16-18H,7,12-15H2,1-6H3;1H/t16?,17-,18+;
InChI key
XZKWIPVTHGWDCF-KUZYQSSXSA-N
Application
Amorolfine hydrochloride has been used as an antifungal agent.
Biochem/physiol Actions
Amorolfine hydrochloride is a potential for treating onychomycosis infected nails by topical application. A 5% solution combination with fluconazole is effective on sensitive fungus in fingernail onychomycosis.
Amorolfine blocks ergosterol biosynthesis by interfering with delta 14 reduction and the delta 7-8 isomerisation.
Amorolfine is a broad-based antifungal agent with fungicidal effects against most fungi, dermatophytes and yeasts.
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signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Chronic 2 - Skin Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable