Quality Level
assay
≥95%
form
powder
optical activity
[α]/D +30 to +40° (c=1; CH2Cl2)
color
white to beige
solubility
DMSO: >10 mg/mL (warmed)
shipped in
wet ice
storage temp.
−20°C
SMILES string
C[C@@H]1CC[C@@]23CCC(=O)[C@H]2[C@]1(C)[C@@H](C[C@@](C)(C=C)[C@@H](O)[C@@H]3C)OC(=O)CO
InChI
1S/C22H34O5/c1-6-20(4)11-16(27-17(25)12-23)21(5)13(2)7-9-22(14(3)19(20)26)10-8-15(24)18(21)22/h6,13-14,16,18-19,23,26H,1,7-12H2,2-5H3/t13-,14+,16-,18+,19+,20-,21+,22+/m1/s1
InChI key
ZRZNJUXESFHSIO-BKUNHTPHSA-N
Biochem/physiol Actions
Pleuromutilin is a diterpene that acts against gram positive bacteria and mycoplasm. It is present in Pleurotus mutilus and Pleurotus passecherianus. Pleuromutilin exhibits its antibacterial action by interfering with the prokaryotic 70S ribosomal subunit and inactivates initiation complex. Pleuromutilin is useful in treating mycoplasma infections in animals.
Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis by binding to bacterial ribosomes in the peptidyl transferase center and inhibiting peptide bond formation.
Pleuromutilin is an antibiotic natural product that inhibits bacterial protein synthesis.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
法规信息
新产品
此项目有
Encyclopedia of Food Sciences and Nutrition (Second Edition), 575-575 (2014)
Thomas J K Findley et al.
Organic & biomolecular chemistry, 9(7), 2433-2451 (2011-02-18)
The cis-hydrindane motif is found in a number of natural products that display important biological activity. A flexible, stereoselective approach to the framework has been developed that features highly diastereoselective, SmI(2)-mediated cyclisations. The strategy has been exploited in the first
Xinyang Wang et al.
Bioorganic & medicinal chemistry letters, 22(19), 6166-6172 (2012-08-31)
Owing to the increasingly serious problems caused by multidrug resistance in community-acquired infection pathogens, it has become an urgent need to develop new classes of antibiotics for overcoming the resistance. In this paper, we describe the design and synthesis of
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML0285-5MG | 04061832633190 |
| SML0285-25MG | 04061832633183 |