SML0338
Lornoxicam
≥98% (HPLC)
别名:
6-Chloro-4-hydroxy-2-methyl-N-2-pyridinyl-2H-thieno[2,3-e]-1,2-thiazine-3-carboxamide 1,1-dioxide, Chlortenoxicam, Ro 13-9297, TS 110
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关于此项目
经验公式（希尔记法）:
C13H10ClN3O4S2
化学文摘社编号:
分子量:
371.82
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Quality Level
assay
≥98% (HPLC)
form
powder
color
faintly yellow to dark yellow
solubility
DMSO: >5 mg/mL (warmed)
storage temp.
−20°C
SMILES string
CN1C(C(=O)Nc2ccccn2)=C(O)c3sc(Cl)cc3S1(=O)=O
InChI
1S/C13H10ClN3O4S2/c1-17-10(13(19)16-9-4-2-3-5-15-9)11(18)12-7(23(17,20)21)6-8(14)22-12/h2-6,18H,1H3,(H,15,16,19)
InChI key
WLHQHAUOOXYABV-UHFFFAOYSA-N
General description
Lornoxicam belongs to the oxicam class. It has anti-inflammatory and antipyretic properties. Lornoxicam prevents the synthesis of prostaglandin (PG) by inhibiting cyclo-oxygenase. It is used to relieve various types of symptoms associated with osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, acute sciatica and low back pain.
Application
Lornoxicam has been used as a drug in melanin binding study with cassette dosing and rapid equilibrium dialysis inserts.
Biochem/physiol Actions
Lornoxicam is an oxicam-class NSAID with strong analgesic properties.
Lornoxicam is an oxicam-class NSAID; cyclooxygenase inhibitor.
signalword
Danger
hcodes
Hazard Classifications
Acute Tox. 2 Oral
存储类别
6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
Zhiyue Zhang et al.
Drug delivery, 18(7), 536-544 (2011-08-05)
Owing to its rationale of targeting the drug to the site of action and minimizing systemic toxic effects of the drug, intra-articular drug delivery system has gained growing interests. In this study, emphasis was placed on intra-articular Lornoxicam-loaded PLGA microspheres
Ali Irfan Guzel et al.
Journal of experimental therapeutics & oncology, 9(4), 317-320 (2012-05-02)
We conducted a study to compare the analgesic effect of oral lornoxicam and oral paracetamol before endometrial sampling for benign conditions. This prospective, double-blind, randomized study was conducted on sixty women underwent endometrial sampling for benign indications, from November 2010
M A Agapov et al.
Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology, (7)(7), 18-23 (2012-03-01)
Acute pancreatitis is a disease of variable severity. In which some patients experience mild, self-limited attacks while others manifest a severe, highly morbid, and frequently lethal attack. The exact mechanisms by which diverse etiological factors induce an attack are still
全球贸易项目编号
| 货号 | GTIN |
|---|---|
| SML0338-50MG | 04061837084324 |
| SML0338-10MG | 04061837084317 |