SML0370
岩白菜素
≥98% (HPLC), runt-related transcription factor 1 (RUNX1) regulator, powder
别名:
2-[（联苯-4-基）氨甲酰基] 苯甲酸, 4′-苯基邻苯二甲酸 (8CI), KGN
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关于此项目
经验公式（希尔记法）:
C20H15NO3
化学文摘社编号:
分子量:
317.34
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
产品名称
岩白菜素, ≥98% (HPLC)
方案
≥98% (HPLC)
表单
powder
溶解性
DMSO: >15 mg/mL
储存温度
room temp
SMILES字符串
O=C(NC1=CC=C(C2=CC=CC=C2)C=C1)C(C=CC=C3)=C3C(O)=O
InChI
1S/C20H15NO3/c22-19(17-8-4-5-9-18(17)20(23)24)21-16-12-10-15(11-13-16)14-6-2-1-3-7-14/h1-13H,(H,21,22)(H,23,24)
InChI key
SLUINPGXGFUMLL-UHFFFAOYSA-N
相关类别
生化/生理作用
Kartogenin 诱导多能间充质干细胞 (MSCs) 选择性分化为软骨细胞。
Kartogenin 诱导多能间充质干细胞 (MSCs) 选择性分化为软骨细胞。Kartogenin 与细丝蛋白 A 结合，破坏了细丝蛋白 A 和 CBFβ 之间的特异性相互作用（核心结合因子 β亚单位）。显然，kartogenin 通过调节 CBFβ 的核定位诱导软骨形成.
Kartogenin是小杂环化合物。它参与Runt相关转录因子1(RUNX1)的调节，在软骨细胞增殖和存活中起重要作用。
储存分类代码
11 - Combustible Solids
WGK
WGK 3
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Tendon-bone junctions (TBJs) are frequently injured, especially in athletic settings. Healing of TBJ injuries is slow and is often repaired with scar tissue formation that compromises normal function. This study explored the feasibility of using kartogenin (KGN), a biocompound, to
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Anti-Müllerian hormone (AMH) is required for proper sexual differentiation by regulating the regression of the Müllerian ducts in males. Recent studies indicate that AMH could be an important factor for maintaining the ovarian reserve. However, the mechanisms of AMH regulation
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