SML0378

Ralfinamide 甲磺酸酯

Name: Ralfinamide 甲磺酸酯
Brand: SIGMA

≥98% (HPLC)

别名:

(2S)-2-[[[4-[(2-Fluorophenyl)methoxy]phenyl]methyl]amino]-propanamide methanesulfonate

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关于此项目

经验公式（希尔记法）:

C₁₇H₁₉FN₂O₂ · CH₃SO₃H

化学文摘社编号:

202825-45-4

分子量:

398.45

NACRES:

NA.77

PubChem Substance ID:

329825378

UNSPSC Code:

12352200

MDL number:

MFCD19690932

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InChI

1S/C17H19FN2O2.CH4O3S/c1-12(17(19)21)20-10-13-6-8-15(9-7-13)22-11-14-4-2-3-5-16(14)18;1-5(2,3)4/h2-9,12,20H,10-11H2,1H3,(H2,19,21);1H3,(H,2,3,4)/t12-;/m0./s1

SMILES string

CS(O)(=O)=O.C[C@H](NCc1ccc(OCc2ccccc2F)cc1)C(N)=O

InChI key

CHQVNINIGBRKGZ-YDALLXLXSA-N

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D 10 to 15° (c=1 HOAc)

color

white to beige

solubility

H₂O: >15 mg/mL

storage temp.

2-8°C

Quality Level

100

Biochem/physiol Actions

Ralfinamide is a mixed sodium and N-type calcium channel blocker.

Ralfinamide is a mixed sodium and N-type calcium channel blocker. Inhibiton is voltage-dependent, with higher potency against inactivated channels. Ralfinamide is two fold selective for tetrodotoxin (TTX)-resistant sodium channels compared with TTX-sensitive currents.

Features and Benefits

This compound is featured on the Calcium Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.