SML0391
SB-268262
≥98% (HPLC)
别名:
(+/-)-SB-273779, N-Methyl-N-(2-methylphenyl)-3-nitro-4-(2-thiazolylsulfinyl)-benzamide
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关于此项目
经验公式（希尔记法）:
C18H15N3O4S2
化学文摘社编号:
分子量:
401.46
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
41106305
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: >5 mg/mL
storage temp.
2-8°C
SMILES string
CN(C(=O)c1ccc(c(c1)[N+]([O-])=O)S(=O)c2nccs2)c3ccccc3C
InChI
1S/C18H15N3O4S2/c1-12-5-3-4-6-14(12)20(2)17(22)13-7-8-16(15(11-13)21(23)24)27(25)18-19-9-10-26-18/h3-11H,1-2H3
InChI key
YXHLPJQQPOMPGE-UHFFFAOYSA-N
Biochem/physiol Actions
SB-268262 is a selective non-peptide antagonist at the CGRP1 receptor.
SB-268262 is a selective non-peptide antagonist at the CGRP1 receptor. SB-268262 inhibits CGRP binding, and CGRP-mediated stimulation of adenylyl cyclase activity in human neuroblastoma cells with IC50 values of 240 and 830 nM, respectively.
Features and Benefits
This compound is featured on the Calcitonin Gene-Related Peptides page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
signalword
Warning
hcodes
Hazard Classifications
Acute Tox. 4 Oral - Eye Irrit. 2
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable