跳转至内容
Merck
CN

主要文件

查看所有文档

SML0392

Dexpramipexole dihydrochloride

≥98% (HPLC)

别名:

(R)-2-Amino-4,5,6,7-tetrahydro-6-(propylamino)benzothiazole dihydrochloride // (R)-Pramipexole dihydrochloride, (R)-4,5,6,7-Tetrahydro-6-(propylamino)-benzothiazole-2-amine dihydrochloride, (R)-Pramipexole dihydrochloride, KNS 760704, R-(+)-Pramipexole dihydrochloride, RPPX, SND 919CL2X

登录 查看组织和合同定价。

选择尺寸

变更视图

关于此项目

经验公式（希尔记法）:
C10H17N3S · 2HCl
化学文摘社编号:
104632-27-1
分子量:
284.25
NACRES:
NA.77
PubChem Substance ID:
329825389
UNSPSC Code:
12352200
MDL number:
MFCD13186799
Assay:
≥98% (HPLC)
Form:
powder
Storage condition:
desiccated
技术服务
需要帮助？我们经验丰富的科学家团队随时乐意为您服务。
让我们为您提供帮助

assay

≥98% (HPLC)

form

powder

optical activity

[α]/D 60 to 70°, c = 1 in methanol

storage condition

desiccated

color

white to beige

solubility

H2O: >15 mg/mL

shipped in

wet ice

storage temp.

−20°C

SMILES string

Cl.Cl.CCCN[C@@H]1CCc2nc(N)sc2C1

InChI

1S/C10H17N3S.2ClH/c1-2-5-12-7-3-4-8-9(6-7)14-10(11)13-8;;/h7,12H,2-6H2,1H3,(H2,11,13);2*1H/t7-;;/m1../s1

InChI key

QMNWXHSYPXQFSK-XCUBXKJBSA-N

Biochem/physiol Actions

R-(+)-Pramipexole is a neuroprotective agent; weak non-ergoline dopamine agonist.
R-(+)-Pramipexole is a neuroprotective agent; weak non-ergoline dopamine agonist. R-(+)-Pramipexole has been found to have neuroprotective effects and is being investigated for treatment of ALS. It reduces mitochondrial reactive oxygen species (ROS) production, inhibits the activation of apoptotic pathways, and increase cell survival in response to a variety of neurotoxins and β-amyloid neurotoxicity. Compared to the S-(-) isomer, R-(+)-Pramipexole has much lower dopamine agonist activity.

Other Notes

Air Sensitive

pictograms

Exclamation mark
GHS07

signalword

Warning

Hazard Classifications

Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

存储类别

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

法规信息

新产品

此项目有

历史批次信息供参考:

分析证书(COA)

Lot/Batch Number
0000027885
0000027340
0000015739
0000015738
0000015306

没有发现合适的版本？

如果您需要特殊版本，可通过批号或批次号查找具体证书。

搜索COA

已有该产品？

在文件库中查找您最近购买产品的文档。

访问文档库

Pawel Licznerski et al.
Cell, 182(5), 1170-1185 (2020-08-17)
Loss of the gene (Fmr1) encoding Fragile X mental retardation protein (FMRP) causes increased mRNA translation and aberrant synaptic development. We find neurons of the Fmr1-/y mouse have a mitochondrial inner membrane leak contributing to a "leak metabolism." In human

商品

Dopamine Receptors

We offer many products related to dopamine receptors for your research needs.

多巴胺受体

我们可提供多种多巴胺受体相关的产品，满足您的各类研究需求。

全球贸易项目编号

货号GTIN
SML0392-10MG04061837084416
SML0392-50MG04061832075648

我们的科学家团队拥有各种研究领域经验，包括生命科学、材料科学、化学合成、色谱、分析及许多其他领域.

联系客户支持