SML0397
DR2313
≥98% (HPLC)
别名:
3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one
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About This Item
经验公式（希尔记法）:
C8H10N2OS
CAS Number:
分子量:
182.24
MDL编号:
UNSPSC代码:
12352200
PubChem化学物质编号:
NACRES:
NA.77
质量水平
方案
≥98% (HPLC)
表单
powder
颜色
white to beige
溶解性
H2O: >2 mg/mL (warmed)
储存温度
2-8°C
SMILES字符串
CC1=NC(=O)C2=C(CCSC2)N1
InChI
1S/C8H10N2OS/c1-5-9-7-2-3-12-4-6(7)8(11)10-5/h2-4H2,1H3,(H,9,10,11)
InChI key
HRYKZAKEAVZGJD-UHFFFAOYSA-N
生化/生理作用
DR2313 is a PARP inhibitor.
DR2313 is a PARP-1; PARP-2 inhibitor (Ki = 0.23 mM). DR2313 has neuroprotective effects in both in vivo and in vitro ischemic models, and reduces cortical infarct volume in focal ischemia in rats.
特点和优势
This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
储存分类代码
11 - Combustible Solids
WGK
WGK 3
闪点(°F)
Not applicable
闪点(°C)
Not applicable
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