SML0397
DR2313
≥98% (HPLC)
别名:
3,5,7,8-Tetrahydro-2-methyl-4H-thiopyrano[4,3-d]pyrimidin-4-one
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关于此项目
经验公式（希尔记法）:
C8H10N2OS
化学文摘社编号:
分子量:
182.24
NACRES:
NA.77
PubChem Substance ID:
UNSPSC Code:
12352200
MDL number:
Assay:
≥98% (HPLC)
Form:
powder
Quality Segment
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
H2O: >2 mg/mL (warmed)
storage temp.
2-8°C
SMILES string
CC1=NC(=O)C2=C(CCSC2)N1
InChI
1S/C8H10N2OS/c1-5-9-7-2-3-12-4-6(7)8(11)10-5/h2-4H2,1H3,(H,9,10,11)
InChI key
HRYKZAKEAVZGJD-UHFFFAOYSA-N
Biochem/physiol Actions
DR2313 is a PARP inhibitor.
DR2313 is a PARP-1; PARP-2 inhibitor (Ki = 0.23 mM). DR2313 has neuroprotective effects in both in vivo and in vitro ischemic models, and reduces cortical infarct volume in focal ischemia in rats.
Features and Benefits
This compound is featured on the Caspases page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.
存储类别
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable